1651 - 1675 of 6570 Results
Title
Year
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OPENTitle: Synthesis and SAR of a novel positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4)Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 19Issue #: 17Start Page: 4967End Page: 4970Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2009.07.072Best OA location URL: http://doi.org/10.1016/j.bmcl.2009.07.072Citation Count: 38
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OPENTitle: Identifying blood-brain-barrier selective single-chain antibody fragmentsJournal Name: Biotechnology JournalPublisher: WileyVol: 9Issue #: 5Start Page: 664End Page: 674Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/biot.201300550Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4073886Citation Count: 23
- Synthesis and SAR of a novel metabotropic glutamate receptor 4 (mGlu4) antagonist: Unexpected ‘molecular switch’ from a closely related mGlu4 positive allosteric modulator2011OPENTitle: Synthesis and SAR of a novel metabotropic glutamate receptor 4 (mGlu4) antagonist: Unexpected ‘molecular switch’ from a closely related mGlu4 positive allosteric modulatorJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 21Issue #: 23Start Page: 6955End Page: 6959Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2011.09.131Citation Count: 18
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OPENTitle: Conformational heterogeneity of the Roc domains in C. tepidum Roc–COR and implications for human LRRK2 Parkinson mutationsJournal Name: Bioscience ReportsPublisher: Portland Press Ltd.Vol: 35Issue #: 5Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1042/bsr20150128Best OA location URL: https://portlandpress.com/bioscirep/article-pdf/35/5/e00254/477473/bsr035e254.pdfCitation Count: 27
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OPENTitle: Isolation and characterization of antibody fragments selective for specific protein morphologies from nanogram antigen samplesJournal Name: Biotechnology ProgressPublisher: WileyVol: 29Issue #: 2Start Page: 463End Page: 471Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/btpr.1698Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3618510Citation Count: 24
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OPENTitle: Striatal Overexpression of ΔJunD Resets L-DOPA-Induced Dyskinesia in a Primate Model of Parkinson DiseaseJournal Name: Biological PsychiatryPublisher: Elsevier BVVol: 66Issue #: 6Start Page: 554End Page: 561Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.biopsych.2009.04.005Best OA location URL: http://doi.org/10.1016/j.biopsych.2009.04.005Citation Count: 97
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OPENTitle: Discovery and characterization of a novel series of N-phenylsulfonyl-1H-pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu4)Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 26Issue #: 13Start Page: 2984End Page: 2987Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2016.05.029Best OA location URL: http://doi.org/10.1016/j.bmcl.2016.05.029Citation Count: 5
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OPENTitle: Normalization and expression changes in predefined sets of proteins using 2D gel electrophoresis: A proteomic study of L-DOPA induced dyskinesia in an animal model of Parkinson's disease using DIGEJournal Name: BMC BioinformaticsPublisher: Springer Science and Business Media LLCVol: 7Issue #: 1Start Page: 475End Page: 475Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/1471-2105-7-475Best OA location URL: https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-475Citation Count: 38
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OPENTitle: Toxic Oligomeric Alpha-Synuclein Variants Present in Human Parkinson’s Disease Brains Are Differentially Generated in Mammalian Cell ModelsJournal Name: BiomoleculesPublisher: MDPI AGVol: 5Issue #: 3Start Page: 1634End Page: 1651Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3390/biom5031634Best OA location URL: http://hdl.handle.net/2286/R.I.43313Citation Count: 40
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OPENTitle: Spatiotemporal Pattern of Striatal ERK1/2 Phosphorylation in a Rat Model of L-DOPA–Induced Dyskinesia and the Role of Dopamine D1 ReceptorsJournal Name: Biological PsychiatryPublisher: Elsevier BVVol: 62Issue #: 7Start Page: 800End Page: 810Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.biopsych.2006.11.032Best OA location URL: http://doi.org/10.1016/j.biopsych.2006.11.032Citation Count: 271
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OPENTitle: GATA transcription factors directly regulate the Parkinson's disease-linked gene α-synucleinJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 105Issue #: 31Start Page: 10907End Page: 10912Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0802437105Best OA location URL: https://www.pnas.org/content/pnas/105/31/10907.full.pdfCitation Count: 268
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OPENTitle: Symptoms of rapid eye movement sleep behavior disorder are associated with cholinergic denervation in Parkinson diseaseJournal Name: Annals of NeurologyPublisher: WileyVol: 71Issue #: 4Start Page: 560End Page: 568Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.22691Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ana.22691Citation Count: 250
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OPENTitle: Validation of nigrostriatal positron emission tomography measures: Critical limitsJournal Name: Annals of NeurologyPublisher: WileyVol: 73Issue #: 3Start Page: 390End Page: 396Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.23798Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3631302Citation Count: 89
- Validation of midbrain positron emission tomography measures for nigrostriatal neurons in macaques2013OPENTitle: Validation of midbrain positron emission tomography measures for nigrostriatal neurons in macaquesJournal Name: Annals of NeurologyPublisher: WileyVol: 74Issue #: 4Start Page: 602End Page: 610Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.23939Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3800272Citation Count: 40
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OPENTitle: N‐acetylcysteine prevents loss of dopaminergic neurons in the EAAC1−/− mouseJournal Name: Annals of NeurologyPublisher: WileyVol: 69Issue #: 3Start Page: 509End Page: 520Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.22162Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ana.22162Citation Count: 138
- Synthesis of the Alzheimer Drug Posiphen into its Primary Metabolic Products (+)-N1-norPosiphen, (+)-N8-norPosiphen and (+)-N1, N8-bisnorPosiphen, their Inhibition of Amyloid Precursor Protein, α -Synuclein Synthesis, Interleukin-1β Release, and Cholinergic Action.2013OPENTitle: Synthesis of the Alzheimer Drug Posiphen into its Primary Metabolic Products (+)-N1-norPosiphen, (+)-N8-norPosiphen and (+)-N1, N8-bisnorPosiphen, their Inhibition of Amyloid Precursor Protein, α -Synuclein Synthesis, Interleukin-1β Release, and Cholinergic Action.Journal Name: Anti-Inflammatory & Anti-Allergy Agents in Medicinal ChemistryPublisher: Bentham Science Publishers Ltd.Vol: 12Issue #: 2Start Page: 117End Page: 128Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.2174/1871523011312020003Citation Count: 28
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OPENTitle: SNCA Variant Associated With Parkinson Disease and Plasma α-Synuclein LevelJournal Name: Archives of NeurologyPublisher: American Medical Association (AMA)Vol: 67Issue #: 11Start Page: 1350End Page: 6Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/archneurol.2010.279Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3010848Citation Count: 178
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OPENTitle: 18F‐flortaucipir tau positron emission tomography distinguishes established progressive supranuclear palsy from controls and Parkinson disease: A multicenter studyJournal Name: Annals of NeurologyPublisher: WileyVol: 82Issue #: 4Start Page: 622End Page: 634Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.25060Best OA location URL: https://escholarship.org/uc/item/01j9450zCitation Count: 175
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OPENTitle: Orientation selective deep brain stimulationJournal Name: Journal of Neural EngineeringPublisher: IOP PublishingVol: 14Issue #: 1Start Page: 016016End Page: 016016Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1088/1741-2552/aa5238Best OA location URL: http://doi.org/10.1088/1741-2552/aa5238Citation Count: 51
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OPENTitle: Myelin Basic Protein-primed T Cells Induce Neurotrophins in Glial Cells via α5β3 IntegrinJournal Name: Journal of Biological ChemistryPublisher: Elsevier BVVol: 282Issue #: 44Start Page: 32222End Page: 32232Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1074/jbc.m702899200Best OA location URL: https://doi.org/10.1074/jbc.m702899200Citation Count: 37
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OPENTitle: Select E2 enzymes differentially regulate parkin activation and mitophagyJournal Name: Journal of Cell SciencePublisher: The Company of BiologistsVol:Issue #:Start Page: 3488End Page: 504Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1242/jcs.147520Best OA location URL: http://doi.org/10.1242/jcs.147520Citation Count: 70
- Cerebral Amyloid Deposition Is Associated with Gait Parameters in the Mayo Clinic Study of Aging2016OPENTitle: Cerebral Amyloid Deposition Is Associated with Gait Parameters in the Mayo Clinic Study of AgingJournal Name: Journal of the American Geriatrics SocietyPublisher: WileyVol: 65Issue #: 4Start Page: 792End Page: 799Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/jgs.14670Best OA location URL: http://doi.org/10.1111/jgs.14670Citation Count: 63
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OPENTitle: Stem cells in development of therapeutics for Parkinson's disease: A perspectiveJournal Name: Journal of Cellular BiochemistryPublisher: WileyVol: 105Issue #: 5Start Page: 1153End Page: 1160Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/jcb.21916Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcb.21916Citation Count: 15
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OPENTitle: Metabolic network expression in parkinsonism: Clinical and dopaminergic correlationsJournal Name: Journal of Cerebral Blood Flow & MetabolismPublisher: SAGE PublicationsVol: 37Issue #: 2Start Page: 683End Page: 693Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1177/0271678x16637880Best OA location URL: https://journals.sagepub.com/doi/pdf/10.1177/0271678X16637880Citation Count: 63
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OPENTitle: The Presence of Select Tau Species in Human Peripheral Tissues and Their Relation to Alzheimer’s DiseaseJournal Name: Journal of Alzheimer's DiseasePublisher: SAGE PublicationsVol: 51Issue #: 2Start Page: 345End Page: 356Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3233/jad-150859Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6074044Citation Count: 96