2101 - 2125 of 6570 Results
Title
Year
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OPENTitle: Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3Journal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 111Issue #: 1Start Page: E34End Page: 43Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1312701111Best OA location URL: https://www.pnas.org/content/pnas/111/1/E34.full.pdfCitation Count: 127
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OPENTitle: In vivo demonstration that α-synuclein oligomers are toxicJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 108Issue #: 10Start Page: 4194End Page: 4199Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1100976108Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3053976Citation Count: 1494
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OPENTitle: Highly pathogenic H5N1 influenza virus can enter the central nervous system and induce neuroinflammation and neurodegenerationJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 106Issue #: 33Start Page: 14063End Page: 14068Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0900096106Best OA location URL: http://doi.org/10.1073/pnas.0900096106Citation Count: 461
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OPENTitle: Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson’s diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 112Issue #: 28Start Page: 8756End Page: 8761Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1509742112Best OA location URL: https://www.pnas.org/content/pnas/112/28/8756.full.pdfCitation Count: 195
- CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivo2015OPENTitle: CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivoJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 112Issue #: 49Start Page: E6818End Page: 24Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1519430112Best OA location URL: https://www.pnas.org/content/pnas/112/49/E6818.full.pdfCitation Count: 30
- Stochastic electrotransport selectively enhances the transport of highly electromobile molecules2015OPENTitle: Stochastic electrotransport selectively enhances the transport of highly electromobile moleculesJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 112Issue #: 46Start Page: E6274End Page: 83Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1510133112Best OA location URL: https://www.pnas.org/content/pnas/112/46/E6274.full.pdfCitation Count: 265
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OPENTitle: Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 110Issue #: 2Start Page: 636End Page: 641Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1220399110Best OA location URL: https://www.pnas.org/content/pnas/110/2/636.full.pdfCitation Count: 210
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OPENTitle: Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic miceJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 111Issue #: 29Start Page: 10732End Page: 10737Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1321785111Best OA location URL: https://www.pnas.org/content/pnas/111/29/10732.full.pdfCitation Count: 343
- Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neurons2016OPENTitle: Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neuronsJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 113Issue #: 47Start Page: E7564End Page: E7571Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1608784113Best OA location URL: https://www.pnas.org/content/pnas/113/47/E7564.full.pdfCitation Count: 60
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OPENTitle: Nrf2 mitigates LRRK2- and α-synuclein–induced neurodegeneration by modulating proteostasisJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 114Issue #: 5Start Page: 1165End Page: 1170Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1522872114Best OA location URL: https://www.pnas.org/content/pnas/114/5/1165.full.pdfCitation Count: 121
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OPENTitle: Parkinson disease-associated mutation R1441H in LRRK2 prolongs the “active state” of its GTPase domainJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 111Issue #: 11Start Page: 4055End Page: 4060Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1323285111Best OA location URL: https://www.pnas.org/content/pnas/111/11/4055.full.pdfCitation Count: 116
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OPENTitle: Improving cerebellar segmentation with statistical fusionJournal Name: SPIE ProceedingsPublisher: SPIEVol: 9784Issue #:Start Page: 97842REnd Page: 97842RPublication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1117/12.2216966Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4845969Citation Count: 7
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OPENTitle: Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrilsJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 129Issue #:Start Page: 67End Page: 78Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2019.05.012Best OA location URL: https://www.sciencedirect.com/science/article/pii/S096999611930124XCitation Count: 75
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OPENTitle: The integrated stress response pathway and neuromodulator signaling in the brain: lessons learned from dystoniaJournal Name: Journal of Clinical InvestigationPublisher: American Society for Clinical InvestigationVol: 134Issue #: 7Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1172/jci177833Best OA location URL: https://doi.org/10.1172/jci177833Citation Count: 17
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OPENTitle: Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegenerationJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 110Issue #: 1Start Page: 300End Page: 305Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1217296110Best OA location URL: https://www.pnas.org/content/pnas/110/1/300.full.pdfCitation Count: 122
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OPENTitle: Intracellular crowding by age-dependent neuromelanin accumulation disrupts neuronal proteostasis and triggers Parkinson disease pathologyJournal Name: AutophagyPublisher: Informa UK LimitedVol: 15Issue #: 11Start Page: 2028End Page: 2030Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1080/15548627.2019.1659621Best OA location URL: https://www.tandfonline.com/doi/pdf/10.1080/15548627.2019.1659621?needAccess=trueCitation Count: 31
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OPENTitle: Cell-attached and Whole-cell Patch-clamp Recordings of Dopamine Neurons in the Substantia Nigra Pars Compacta of Mouse Brain SlicesJournal Name: BIO-PROTOCOLPublisher: Bio-Protocol, LLCVol: 11Issue #: 15Start Page: e4109End Page: e4109Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.21769/bioprotoc.4109Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8376493Citation Count: 2
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OPENTitle: Correlates of deep brain stimulation consensus conference decision to treat primary dystoniaJournal Name: Clinical Neurology and NeurosurgeryPublisher: Elsevier BVVol: 207Issue #:Start Page: 106747End Page: 106747Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.clineuro.2021.106747Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8386520Citation Count: 9
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OPENTitle: Identification of Drugs Associated with Lower Risk of Parkinson’s Disease Using a Systematic Screening Approach in a Nationwide Nested Case–Control StudyJournal Name: Clinical EpidemiologyPublisher: Informa UK LimitedVol: Volume 14Issue #:Start Page: 1217End Page: 1227Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.2147/clep.s381289Best OA location URL: https://www.dovepress.com/getfile.php?fileID=84998Citation Count: 14
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OPENTitle: CD4 + T cells contribute to neurodegeneration in Lewy body dementiaJournal Name: SciencePublisher: American Association for the Advancement of Science (AAAS)Vol: 374Issue #: 6569Start Page: 868End Page: 874Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1126/science.abf7266Best OA location URL: https://escholarship.org/uc/item/7h341961Citation Count: 221
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OPENTitle: Determinants of Self-Stigma in People with Parkinson’s Disease: A Mixed Methods Scoping ReviewJournal Name: Journal of Parkinson's DiseasePublisher: SAGE PublicationsVol: 12Issue #: 2Start Page: 509End Page: 522Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3233/jpd-212869Best OA location URL: https://content.iospress.com:443/download/journal-of-parkinsons-disease/jpd212869?id=journal-of-parkinsons-disease%2Fjpd212869Citation Count: 19
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OPENTitle: Predicting Parkinson’s Disease and Its Pathology via Simple Clinical VariablesJournal Name: Journal of Parkinson's DiseasePublisher: SAGE PublicationsVol: 12Issue #: 1Start Page: 341End Page: 351Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.3233/jpd-212876Best OA location URL: https://escholarship.org/uc/item/8ks0w86mCitation Count: 12
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OPENTitle: Caspase-1 causes truncation and aggregation of the Parkinson’s disease-associated protein α-synucleinJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 113Issue #: 34Start Page: 9587End Page: 9592Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1610099113Best OA location URL: https://www.pnas.org/content/pnas/113/34/9587.full.pdfCitation Count: 266
- α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation2015OPENTitle: α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylationJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 112Issue #: 15Start Page: E1926End Page: 35Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1417883112Best OA location URL: https://www.pnas.org/content/pnas/112/15/E1926.full.pdfCitation Count: 150
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OPENTitle: Age-dependent alterations in key components of the nigrostriatal dopaminergic system and distinct motor phenotypesJournal Name: Acta Pharmacologica SinicaPublisher: Springer Science and Business Media LLCVol: 43Issue #: 4Start Page: 862End Page: 875Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/s41401-021-00713-5Best OA location URL: https://www.nature.com/articles/s41401-021-00713-5.pdfCitation Count: 9