9101 - 9145 of 9145 Results
Title
Year
- Global cellular proteo-lipidomic profiling of diverse lysosomal storage disease mutants using nMOST2025OPENTitle: Global cellular proteo-lipidomic profiling of diverse lysosomal storage disease mutants using nMOSTJournal Name: Science AdvancesPublisher: American Association for the Advancement of Science (AAAS)Vol: 11Issue #: 4Start Page: eadu5787End Page: eadu5787Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1126/sciadv.adu5787Best OA location URL: https://doi.org/10.1126/sciadv.adu5787Citation Count: 5
-
OPENTitle: Type II kinase inhibitors that target Parkinson’s disease–associated LRRK2Journal Name: Science AdvancesPublisher: American Association for the Advancement of Science (AAAS)Vol: 11Issue #: 23Start Page: eadt2050End Page: eadt2050Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1126/sciadv.adt2050Best OA location URL: http://www.eubopen.org/sites/www.eubopen.org/files/attachments/2021/DSF-inhibitorScreening_v1.pdfCitation Count: 18
-
OPENTitle: CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiologyJournal Name: Science AdvancesPublisher: American Association for the Advancement of Science (AAAS)Vol: 11Issue #: 46Start Page: eadu0726End Page: eadu0726Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1126/sciadv.adu0726Best OA location URL: https://doi.org/10.1126/sciadv.adu0726Citation Count: 3
-
OPENTitle: A long-lived pool of PINK1 imparts a molecular memory of depolarization-induced activityJournal Name: Science AdvancesPublisher: American Association for the Advancement of Science (AAAS)Vol: 11Issue #: 9Start Page: eadr1938End Page: eadr1938Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1126/sciadv.adr1938Best OA location URL: https://doi.org/10.1126/sciadv.adr1938Citation Count: 3
-
OPENTitle: Alpha-synuclein regulates nucleolar DNA double-strand break repair in melanomaJournal Name: Science AdvancesPublisher: American Association for the Advancement of Science (AAAS)Vol: 11Issue #: 15Start Page: eadq2519End Page: eadq2519Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1126/sciadv.adq2519Best OA location URL: https://doi.org/10.1126/sciadv.adq2519Citation Count: 8
-
OPENTitle: Astrocytic RNA editing regulates the host immune response to alpha-synucleinJournal Name: Science AdvancesPublisher: American Association for the Advancement of Science (AAAS)Vol: 11Issue #: 15Start Page: eadp8504End Page: eadp8504Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1126/sciadv.adp8504Best OA location URL: https://doi.org/10.1126/sciadv.adp8504Citation Count: 11
-
OPENTitle: Combining biomarkers for prognostic modelling of Parkinson’s diseaseJournal Name: Journal of Neurology, Neurosurgery & PsychiatryPublisher: BMJVol: 93Issue #: 7Start Page: 707End Page: 715Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1136/jnnp-2021-328365Best OA location URL: https://jnnp.bmj.com/content/jnnp/93/7/707.full.pdfCitation Count: 30
-
OPENTitle: Oligogenic structure of amyotrophic lateral sclerosis has genetic testing, counselling and therapeutic implicationsJournal Name: Journal of Neurology, Neurosurgery & PsychiatryPublisher: BMJVol: 96Issue #: 10Start Page: 928End Page: 936Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1136/jnnp-2024-335364Best OA location URL: https://jnnp.bmj.com/content/jnnp/early/2025/02/12/jnnp-2024-335364.full.pdfCitation Count: 17
- Oxygen-induced stress reveals context-specific gene regulatory effects in human brain organoids2025OPENTitle: Oxygen-induced stress reveals context-specific gene regulatory effects in human brain organoidsJournal Name: Genome ResearchPublisher: Cold Spring Harbor LaboratoryVol: 35Issue #: 8Start Page: 1689End Page: 1700Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1101/gr.280219.124Best OA location URL: http://genome.cshlp.org/content/early/2025/06/02/gr.280219.124.full.pdfCitation Count: 9
-
OPENTitle: Assessing DNA methylation detection for primary human tissue using Nanopore sequencingJournal Name: Genome ResearchPublisher: Cold Spring Harbor LaboratoryVol: 35Issue #: 4Start Page: 632End Page: 643Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1101/gr.279159.124Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/12047266Citation Count: 9
-
OPENTitle: Transcriptional programs mediating neuronal toxicity and altered glial–neuronal signaling in a Drosophila knock-in tauopathy modelJournal Name: Genome ResearchPublisher: Cold Spring Harbor LaboratoryVol:Issue #:Start Page: 590End Page: 605Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1101/gr.278576.123Best OA location URL: https://genome.cshlp.org/content/early/2024/04/09/gr.278576.123.full.pdfCitation Count: 10
- Brain atrophy in prodromal synucleinopathy is shaped by structural connectivity and gene expression2022OPENTitle: Brain atrophy in prodromal synucleinopathy is shaped by structural connectivity and gene expressionJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 145Issue #: 9Start Page: 3162End Page: 3178Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/brain/awac187Best OA location URL: https://academic.oup.com/brain/article-pdf/145/9/3162/45824139/awac187.pdfCitation Count: 52
-
OPENTitle: Cortical connectivity of the nucleus basalis of Meynert in Parkinson’s disease and Lewy body dementiasJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 144Issue #: 3Start Page: 781End Page: 788Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1093/brain/awaa411Best OA location URL: https://academic.oup.com/brain/article-pdf/144/3/781/37036696/awaa411.pdfCitation Count: 42
- The contribution of apolipoprotein E genetic variation to dementia risk in British South Asians2026OPENTitle: The contribution of apolipoprotein E genetic variation to dementia risk in British South AsiansJournal Name: Brain CommunicationsPublisher: Oxford University Press (OUP)Vol: 8Issue #: 3Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1093/braincomms/fcag141Best OA location URL: https://doi.org/10.1093/braincomms/fcag141Citation Count: 0
-
OPENTitle: Predicting longitudinal brain atrophy in Parkinson’s disease using a Susceptible-Infected-Removed agent-based modelJournal Name: Network NeurosciencePublisher: MIT PressVol: 7Issue #: 3Start Page: 906End Page: 925Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1162/netn_a_00296Best OA location URL: https://direct.mit.edu/netn/article-pdf/doi/10.1162/netn_a_00296/2074404/netn_a_00296.pdfCitation Count: 19
- Exploring [11C]CPPC as a CSF1R-targeted PET imaging marker for early Parkinson’s disease severity2025OPENTitle: Exploring [11C]CPPC as a CSF1R-targeted PET imaging marker for early Parkinson’s disease severityJournal Name: Journal of Clinical InvestigationPublisher: American Society for Clinical InvestigationVol: 135Issue #: 12Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1172/jci186591Best OA location URL: http://www.jci.org/articles/view/186591/files/pdfCitation Count: 8
-
OPENTitle: Tagless LysoIP for immunoaffinity enrichment of native lysosomes from clinical samplesJournal Name: Journal of Clinical InvestigationPublisher: American Society for Clinical InvestigationVol: 135Issue #: 4Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1172/jci183592Best OA location URL: http://www.jci.org/articles/view/183592/files/pdfCitation Count: 12
-
OPENTitle: PINK1 is a target of T cell responses in Parkinson’s diseaseJournal Name: Journal of Clinical InvestigationPublisher: American Society for Clinical InvestigationVol: 135Issue #: 4Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1172/jci180478Best OA location URL: http://www.jci.org/articles/view/180478/files/pdfCitation Count: 21
-
OPENTitle: Cognition and future depression: associations with risk in those with and without a history of depressionJournal Name: BMJ Mental HealthPublisher: BMJVol: 29Issue #: 1Start Page: e302332End Page: e302332Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1136/bmjment-2025-302332Best OA location URL: https://doi.org/10.1136/bmjment-2025-302332Citation Count: 0
-
OPENTitle: An individualized tractography pipeline for the nucleus basalis of Meynert lateral tractJournal Name: Imaging NeurosciencePublisher: MIT PressVol: 2Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1162/imag_a_00067Best OA location URL: https://direct.mit.edu/imag/article-pdf/doi/10.1162/imag_a_00067/2200468/imag_a_00067.pdfCitation Count: 1
- Structural remodeling of the mitochondrial protein biogenesis machinery under proteostatic stress2026OPENTitle: Structural remodeling of the mitochondrial protein biogenesis machinery under proteostatic stressJournal Name: Science AdvancesPublisher: American Association for the Advancement of Science (AAAS)Vol: 12Issue #: 10Start Page: eaed3579End Page: eaed3579Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1126/sciadv.aed3579Best OA location URL: http://www.promega.com/-/media/files/resources/protocols/technical-manuals/101/celltiterglo-2-0-assay-protocol.pdfCitation Count: 4
-
OPENTitle: An enhanced mountain climbing search algorithm to enable fast and accurate autofocusing in high resolution fluorescence microscopyJournal Name: Methods and Applications in FluorescencePublisher: IOP PublishingVol: 13Issue #: 4Start Page: 045001End Page: 045001Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1088/2050-6120/ae008fBest OA location URL: https://doi.org/10.1088/2050-6120/ae008fCitation Count: 1
-
OPENTitle: Detecting rhythmic spiking through the power spectra of point process model residualsJournal Name: Journal of Neural EngineeringPublisher: IOP PublishingVol: 21Issue #: 4Start Page: 046041End Page: 046041Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1088/1741-2552/ad6188Best OA location URL: https://doi.org/10.1088/1741-2552/ad6188Citation Count: 5
-
OPENTitle: Movement-related activity in the internal globus pallidus of the parkinsonian macaqueJournal Name: Journal of NeurophysiologyPublisher: American Physiological SocietyVol: 134Issue #: 2Start Page: 741End Page: 765Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1152/jn.00611.2024Best OA location URL: https://doi.org/10.1152/jn.00611.2024Citation Count: 0
-
OPENTitle: Inhibition of striatal dopamine release by the L‐type calcium channel inhibitor isradipine co‐varies with risk factors for Parkinson'sJournal Name: European Journal of NeurosciencePublisher: WileyVol: 59Issue #: 6Start Page: 1242End Page: 1259Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1111/ejn.16180Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ejn.16180Citation Count: 9
-
OPENTitle: The pyrethroid insecticide deltamethrin disrupts neuropeptide and monoamine signaling pathways in the gastrointestinal tractJournal Name: Toxicological SciencesPublisher: Oxford University Press (OUP)Vol: 207Issue #: 1Start Page: 208End Page: 220Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1093/toxsci/kfaf076Best OA location URL: https://academic.oup.com/toxsci/advance-article-pdf/doi/10.1093/toxsci/kfaf076/63590255/kfaf076.pdfCitation Count: 3
- Observation of an α-synuclein liquid droplet state and its maturation into Lewy body-like assemblies2020OPENTitle: Observation of an α-synuclein liquid droplet state and its maturation into Lewy body-like assembliesJournal Name: Journal of Molecular Cell BiologyPublisher: Oxford University Press (OUP)Vol:Issue #:Start Page: 282End Page: 294Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/jmcb/mjaa075Best OA location URL: https://academic.oup.com/jmcb/article-pdf/13/4/282/39569504/mjaa075.pdfCitation Count: 104
-
OPENTitle: PBMCpedia: a harmonized PBMC scRNA-seq database with unified mapping and enhanced celltype annotationJournal Name: Nucleic Acids ResearchPublisher: Oxford University Press (OUP)Vol: 54Issue #: D1Start Page: D1216End Page: D1221Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1093/nar/gkaf1245Best OA location URL: https://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gkaf1245/65488636/gkaf1245.pdfCitation Count: 2
-
OPENTitle: Mapping of a N-terminal α-helix domain required for human PINK1 stabilization, Serine228 autophosphorylation and activation in cellsJournal Name: Open BiologyPublisher: The Royal SocietyVol: 12Issue #: 1Start Page: 210264End Page: 210264Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1098/rsob.210264Best OA location URL: https://doi.org/10.1098/rsob.210264Citation Count: 47
-
OPENTitle: Neuropsychiatric symptoms cluster and fluctuate over time in behavioral variant frontotemporal dementiaJournal Name: Psychiatry and Clinical NeurosciencesPublisher: WileyVol: 79Issue #: 6Start Page: 327End Page: 335Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/pcn.13810Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/pcn.13810Citation Count: 9
-
OPENTitle: Mechanism of human PINK1 activation at the TOM complex in a reconstituted systemJournal Name: Science AdvancesPublisher: American Association for the Advancement of Science (AAAS)Vol: 10Issue #: 23Start Page: eadn7191End Page: eadn7191Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc, cc-by-ncDOI - Digital Object Identifier: 10.1126/sciadv.adn7191Best OA location URL: https://www.science.org/doi/pdf/10.1126/sciadv.adn7191?download=trueCitation Count: 40
-
OPENTitle: Kinome screening identifies integrated stress response kinase EIF2AK1/HRI as a negative regulator of PINK1 mitophagy signalingJournal Name: Science AdvancesPublisher: American Association for the Advancement of Science (AAAS)Vol: 11Issue #: 19Start Page: eadn2528End Page: eadn2528Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc, cc-by-ncDOI - Digital Object Identifier: 10.1126/sciadv.adn2528Best OA location URL: https://doi.org/10.1126/sciadv.adn2528Citation Count: 8
-
OPENTitle: Phosphoglycerate kinase is a central leverage point in Parkinson’s disease–driven neuronal metabolic deficitsJournal Name: Science AdvancesPublisher: American Association for the Advancement of Science (AAAS)Vol: 10Issue #: 34Start Page: eadn6016End Page: eadn6016Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1126/sciadv.adn6016Best OA location URL: https://doi.org/10.1126/sciadv.adn6016Citation Count: 30
-
OPENTitle: The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1Journal Name: Science AdvancesPublisher: American Association for the Advancement of Science (AAAS)Vol: 10Issue #: 26Start Page: eadk1296End Page: eadk1296Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc, cc-by-ncDOI - Digital Object Identifier: 10.1126/sciadv.adk1296Best OA location URL: https://doi.org/10.1126/sciadv.adk1296Citation Count: 25
- Anionic nanoplastic contaminants promote Parkinson’s disease–associated α-synuclein aggregation2023OPENTitle: Anionic nanoplastic contaminants promote Parkinson’s disease–associated α-synuclein aggregationJournal Name: Science AdvancesPublisher: American Association for the Advancement of Science (AAAS)Vol: 9Issue #: 46Start Page: eadi8716End Page: eadi8716Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1126/sciadv.adi8716Best OA location URL: https://doi.org/10.1126/sciadv.adi8716Citation Count: 222
- LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification2023OPENTitle: LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversificationJournal Name: Science AdvancesPublisher: American Association for the Advancement of Science (AAAS)Vol: 9Issue #: 44Start Page: eadh9543End Page: eadh9543Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1126/sciadv.adh9543Best OA location URL: https://doi.org/10.1126/sciadv.adh9543Citation Count: 71
- Normative trajectories of R1, R2*, and magnetic susceptibility in basal ganglia on healthy ageing2025OPENTitle: Normative trajectories of R1, R2*, and magnetic susceptibility in basal ganglia on healthy ageingJournal Name: Imaging NeurosciencePublisher: MIT PressVol: 3Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1162/imag_a_00456Best OA location URL: https://doi.org/10.1162/imag_a_00456Citation Count: 2
-
OPENTitle: RGS10 attenuates systemic immune dysregulation induced by chronic inflammatory stressJournal Name: Journal of NeuroinflammationPublisher: Springer Science and Business Media LLCVol: 22Issue #: 1Start Page: 49End Page: 49Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s12974-024-03322-1Best OA location URL: https://doi.org/10.1186/s12974-024-03322-1Citation Count: 0
-
OPENTitle: PINOT: an intuitive resource for integrating protein-protein interactionsJournal Name: Cell Communication and SignalingPublisher: Springer Science and Business Media LLCVol: 18Issue #: 1Start Page: 92End Page: 92Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1186/s12964-020-00554-5Best OA location URL: https://biosignaling.biomedcentral.com/track/pdf/10.1186/s12964-020-00554-5Citation Count: 42
-
OPENTitle: Parkinson’s disease LRRK2 mutations dysregulate iron homeostasis and promote oxidative stress and ferroptosis in human neurons and astrocytesJournal Name: Molecular NeurodegenerationPublisher: Springer Science and Business Media LLCVol:Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13024-026-00979-5Best OA location URL: https://doi.org/10.1186/s13024-026-00979-5Citation Count: 2
- A novel alpha-synuclein G14R missense variant is associated with atypical neuropathological features2025OPENTitle: A novel alpha-synuclein G14R missense variant is associated with atypical neuropathological featuresJournal Name: Molecular NeurodegenerationPublisher: Springer Science and Business Media LLCVol: 20Issue #: 1Start Page: 98End Page: 98Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13024-025-00889-yBest OA location URL: https://molecularneurodegeneration.biomedcentral.com/counter/pdf/10.1186/s13024-025-00889-yCitation Count: 3
-
OPENTitle: Whole-genome sequencing analysis reveals new susceptibility loci and structural variants associated with progressive supranuclear palsyJournal Name: Molecular NeurodegenerationPublisher: Springer Science and Business Media LLCVol: 19Issue #: 1Start Page: 61End Page: 61Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13024-024-00747-3Best OA location URL: https://molecularneurodegeneration.biomedcentral.com/counter/pdf/10.1186/s13024-024-00747-3Citation Count: 26
-
OPENTitle: Selective molecular and network architecture features underlie brain cortical atrophy in dementia with Lewy bodiesJournal Name: Journal of Biomedical SciencePublisher: Springer Science and Business Media LLCVol: 33Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s12929-026-01267-6Best OA location URL: https://link.springer.com/content/pdf/10.1186/s12929-026-01267-6.pdfCitation Count: 0
-
OPENTitle: Cache: Utilizing ultra-large library screening in Rosetta to identify novel binders of the WD-repeat domain of Leucine-Rich Repeat Kinase 2Journal Name: Journal of CheminformaticsPublisher: Springer Science and Business Media LLCVol: 17Issue #: 1Start Page: 145End Page: 145Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13321-025-01084-3Best OA location URL: https://jcheminf.biomedcentral.com/counter/pdf/10.1186/s13321-025-01084-3Citation Count: 3
-
OPENTitle: Impairment of neuronal activity occurs at the early stages of the aggregation cascade of Aβ1-42 and mutant TauJournal Name: Disease Models & MechanismsPublisher: The Company of BiologistsVol: 19Issue #: 3Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1242/dmm.052295Best OA location URL: https://doi.org/10.1242/dmm.052295Citation Count: 0