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MJFF Publications

7651 - 7700 of 9145 Results
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  • Summary Details
    OPEN
    Title: Characterization of TAE684 as a potent LRRK2 kinase inhibitor
    Journal Name: Bioorganic & Medicinal Chemistry Letters
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.bmcl.2012.01.084
    Citation Count: 88
  • Summary Details
    OPEN
    Title: Genetic and Clinical Features of Progranulin-Associated Frontotemporal Lobar Degeneration
    Journal Name: Archives of Neurology
    Publisher: American Medical Association (AMA)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1001/archneurol.2011.53
    Citation Count: 121
  • Summary Details
    OPEN
    Title: Large-scale replication and heterogeneity in Parkinson disease genetic loci
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1212/wnl.0b013e318264e353
    Citation Count: 132
  • Summary Details
    OPEN
    Title: Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1318306111
    Citation Count: 367
  • Summary Details
    OPEN
    Title: Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1
    Journal Name: The EMBO Journal
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.15252/embj.201591593
    Citation Count: 187
  • Proteomic identification of proteins in the human brain: Towards a more comprehensive understanding of neurodegenerative disease
    2008
    Summary Details
    OPEN
    Title: Proteomic identification of proteins in the human brain: Towards a more comprehensive understanding of neurodegenerative disease
    Journal Name: PROTEOMICS – Clinical Applications
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/prca.200800043
    Citation Count: 27
  • Summary Details
    OPEN
    Title: Integrative Pathway-Based Approach for Genome-Wide Association Studies: Identification of New Pathways for Rheumatoid Arthritis and Type 1 Diabetes
    Journal Name: PLoS ONE
    Publisher: Public Library of Science (PLoS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pone.0078577
    Citation Count: 10
  • Summary Details
    RESTRICTED
    Title: Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0501282102
    Citation Count: 708
  • Summary Details
    OPEN
    Title: Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions
    Journal Name: Nature Genetics
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/ng.536
    Best OA location URL: http://doi.org/10.1038/ng.536
    Citation Count: 612
  • Summary Details
    OPEN
    Title: The microbiome of the human lower airways: a next generation sequencing perspective
    Journal Name: World Allergy Organization Journal
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1186/s40413-015-0074-z
    Citation Count: 46
  • Summary Details
    OPEN
    Title: Molecular markers of early Parkinson's disease based on gene expression in blood
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0610204104
    Citation Count: 517
  • Summary Details
    OPEN
    Title: α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1417883112
    Citation Count: 150
  • Summary Details
    OPEN
    Title: Stochastic electrotransport selectively enhances the transport of highly electromobile molecules
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1510133112
    Citation Count: 265
  • Summary Details
    OPEN
    Title: CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivo
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1519430112
    Citation Count: 30
  • Summary Details
    OPEN
    Title: Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson’s disease
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1509742112
    Citation Count: 195
  • Summary Details
    OPEN
    Title: Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1312701111
    Citation Count: 127
  • Summary Details
    OPEN
    Title: Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1220399110
    Citation Count: 210
  • Summary Details
    OPEN
    Title: Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases
    Journal Name: Human Molecular Genetics
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/hmg/dds161
    Citation Count: 237
  • Summary Details
    OPEN
    Title: Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1321845111
    Citation Count: 215
  • Summary Details
    OPEN
    Title: Parkinson disease-associated mutation R1441H in LRRK2 prolongs the “active state” of its GTPase domain
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1323285111
    Citation Count: 116
  • Summary Details
    OPEN
    Title: Caspase-1 causes truncation and aggregation of the Parkinson’s disease-associated protein α-synuclein
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1610099113
    Citation Count: 266
  • Summary Details
    OPEN
    Title: Directed Differentiation of Dopaminergic Neuronal Subtypes from Human Embryonic Stem Cells
    Journal Name: STEM CELLS
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1634/stemcells.2004-0365
    Citation Count: 490
  • Summary Details
    OPEN
    Title: Rapid Generation of Functional Dopaminergic Neurons From Human Induced Pluripotent Stem Cells Through a Single-Step Procedure Using Cell Lineage Transcription Factors
    Journal Name: Stem Cells Translational Medicine
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.5966/sctm.2012-0133
    Citation Count: 97
  • Summary Details
    OPEN
    Title: Advances in Therapeutic Options for Gait and Balance in Parkinson’s Disease
    Journal Name: US Neurology
    Publisher: Touch Medical Media, Ltd.
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.17925/usn.2011.07.02.100
    Citation Count: 20
  • Summary Details
    OPEN
    Title: Impaired dopamine release and synaptic plasticity in the striatum of PINK1 -deficient mice
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0702717104
    Citation Count: 539
  • Summary Details
    OPEN
    Title: Venous Thromboembolism during Interventional MRI-Guided Stereotactic Surgery
    Journal Name: Stereotactic and Functional Neurosurgery
    Publisher: S. Karger AG
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1159/000486642
    Citation Count: 0
  • Summary Details
    OPEN
    Title: Improving cerebellar segmentation with statistical fusion
    Journal Name: SPIE Proceedings
    Publisher: SPIE
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1117/12.2216966
    Citation Count: 7
  • Summary Details
    OPEN
    Title: Regulation of myeloid cell phagocytosis by LRRK2 via WAVE2 complex stabilization is altered in Parkinson’s disease
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1718946115
    Citation Count: 118
  • Summary Details
    RESTRICTED
    Title: Multi-modal and targeted imaging improves automated mid-brain segmentation
    Journal Name: SPIE Proceedings
    Publisher: SPIE
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1117/12.2254428
    Citation Count: 4
  • Summary Details
    RESTRICTED
    Title: Multi-scale hippocampal parcellation improves atlas-based segmentation accuracy
    Journal Name: SPIE Proceedings
    Publisher: SPIE
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1117/12.2254425
    Citation Count: 17
  • Summary Details
    OPEN
    Title: Nrf2 mitigates LRRK2- and α-synuclein–induced neurodegeneration by modulating proteostasis
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1522872114
    Citation Count: 121
  • Summary Details
    OPEN
    Title: Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1321785111
    Citation Count: 343
  • Summary Details
    OPEN
    Title: Identification of a highly neurotoxic α-synuclein species inducing mitochondrial damage and mitophagy in Parkinson’s disease
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1713849115
    Citation Count: 231
  • Summary Details
    OPEN
    Title: Alterations of p11 in brain tissue and peripheral blood leukocytes in Parkinson’s disease
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1621218114
    Citation Count: 40
  • Proteomics of human cerebrospinal fluid – the good, the bad, and the ugly
    2007
    Summary Details
    RESTRICTED
    Title: Proteomics of human cerebrospinal fluid – the good, the bad, and the ugly
    Journal Name: PROTEOMICS – Clinical Applications
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/prca.200700081
    Citation Count: 60
  • Summary Details
    OPEN
    Title: Cerebral blood flow in Alzheimer’s disease
    Journal Name: Vascular Health and Risk Management
    Publisher: Informa UK Limited
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.2147/vhrm.s34874
    Citation Count: 200
  • Summary Details
    OPEN
    Title: Neuroprotective activities of regulatory T cells
    Journal Name: Trends in Molecular Medicine
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.molmed.2011.08.005
    Citation Count: 55
  • A soluble α-synuclein construct forms a dynamic tetramer
    2011
    Summary Details
    RESTRICTED
    Title: A soluble α-synuclein construct forms a dynamic tetramer
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1113260108
    Citation Count: 466
  • Summary Details
    OPEN
    Title: Novel Para-Phenyl Substituted Diindolylmethanes Protect Against MPTP Neurotoxicity and Suppress Glial Activation in a Mouse Model of Parkinson’s Disease
    Journal Name: Toxicological Sciences
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/toxsci/kfu236
    Citation Count: 51
  • Summary Details
    OPEN
    Title: Behavioral and histopathological consequences of paraquat intoxication in mice: Effects of α‐synuclein over‐expression
    Journal Name: Synapse
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/syn.20456
    Citation Count: 190
  • Summary Details
    OPEN
    Title: Parkin Mutations Reduce the Complexity of Neuronal Processes in iPSC-Derived Human Neurons
    Journal Name: Stem Cells
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/stem.1854
    Citation Count: 112
  • Summary Details
    OPEN
    Title: Genetic variation of Omi/HtrA2 and Parkinson's disease
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2008.08.003
    Citation Count: 72
  • Summary Details
    OPEN
    Title: Selective inhibition of NF-κB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0704908104
    Citation Count: 435
  • Summary Details
    OPEN
    Title: Vagus Nerve Stimulation During Rehabilitative Training Improves Functional Recovery After Intracerebral Hemorrhage
    Journal Name: Stroke
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1161/strokeaha.114.006654
    Citation Count: 154
  • Summary Details
    OPEN
    Title: About miRNAs, miRNA seeds, target genes and target pathways
    Journal Name: Oncotarget
    Publisher: Impact Journals, LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.18632/oncotarget.22363
    Citation Count: 162
  • Summary Details
    OPEN
    Title: Slow progressive degeneration of nigral dopaminergic neurons in postnatal Engrailed mutant mice
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0602116103
    Citation Count: 139
  • Summary Details
    OPEN
    Title: Using global statistical tests in long‐term Parkinson's disease clinical trials
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.22645
    Citation Count: 43
  • Essential tremor and Parkinson's disease: Lack of a link
    2011
    Summary Details
    RESTRICTED
    Title: Essential tremor and Parkinson's disease: Lack of a link
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23509
    Citation Count: 57
  • Summary Details
    OPEN
    Title: Physiology versus pathology in Parkinson's disease
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0704254104
    Citation Count: 11
  • Summary Details
    OPEN
    Title: Racial differences may influence the role of cholecystokinin polymorphisms in Parkinson's disease hallucinations
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23655
    Citation Count: 19
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