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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2020
    Alpha-synuclein Toxicity in LRRK2 Knock-in Models and Rescue by LRRK2 Silencing

    Study Rationale:
    Gene mutations that alter the function of the LRRK2 protein are known to increase the risk of developing Parkinson’s disease (PD). One of the pathological hallmarks of PD is the...

  • Therapeutic Pipeline Program, 2020
    Novel Candidate against Alpha-synuclein for the Treatment of Parkinson’s Disease

    Study Rationale:
    The goal of this program is to develop a novel drug for Parkinson’s disease with a unique mechanism of action. We have a drug candidate that shows potential as an inhibitor of alpha...

  • Therapeutic Pipeline Program, 2020
    Photoreceptor-Directed Light Therapy in Parkinson’s Disease

    Study Rationale:    
    Non-motor symptoms including sleep disturbances are common and enormously impact quality of life in people with Parkinson’s disease (PD). Sleep disruption affects motor function...

  • Research Grant Supplement, 2020
    Discovery of Selective PET Imaging Agents for Tauopathies and Alpha-Synuclein

    Study Rationale:    
    The development of alpha-synuclein and tau imaging agents will be valuable for people with Parkinson’s disease and Frontal Temporal Dementia (FTD), as deposits of these proteins...

  • Research Grant, 2020
    Parkinson’s Disease Subtyping by Genetic and Intestinal Inflammation Biomarkers

    Study Rationale: 
    Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide. Currently, no drugs are available to treat or prevent the disease because the processes...

  • Biosample Use Program, 2020
    Adaptive Immune Markers for Predicting Cognitive Decline in Parkinson’s Disease

    Study Rationale:    
    For reasons not well understood, people with Parkinson's disease are at risk for developing dementia, a decline in memory, thinking and/or language abilities severe enough to...

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Our funding programs support basic, translational and clinical research from academia and industry.

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