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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2022
    Using a Systems-based Approach to Study the Molecular Processes Underlying Parkinson’s Disease: The Foundational Data Initiative

    Study Rationale: This effort aims to produce foundational data that will provide immediate insight and a resource for understanding the molecular basis of Parkinson disease (PD). The work, conducted...

  • Alpha-synuclein Seed Amplification Assay Program, 2022
    Comparison and Cross-Validation of Alpha-synuclein Seed Aggregation Assays in Samples of Skin, Cerebrospinal Fluid, Saliva and Tears

    Study Rationale: Identification of misfolded alpha-synuclein aggregates in postmortem brain samples remains a major histopathological hallmark for confirming the diagnosis of Parkinson’s disease (PD)...

  • Diversity, Equity and Inclusivity in Parkinson's research, 2022
    Overcoming Inequity in the Treatment of Parkinson’s Disease: Recognizing and Caring for Underserved Communities in Brazil

    Study Rationale: Brazil has enormous economic and social inequalities. Pesticides, heavy metals and other pollutants can contribute to the development of degenerative conditions such as Parkinson's...

  • Diversity, Equity and Inclusivity in Parkinson's research, 2022
    Studying Parkinson’s Disease Clinical Features, Progression and Quality of Care in Latino Patients from a Population-based Epidemiological Study in the United States

    Study Rationale: Social and medical factors can affect the rates of Parkinson’s disease (PD) and how the disorder manifests in different individuals. These factors may carry different weight in...

  • [RFA] Use of PD Biosamples - Spring 2020, 2022
    Studying DNA Methylation in Parkinson’s Disease Using the Systemic Synuclein Sampling Study

    Study Rationale: Developing accurate and reliable biomarkers for Parkinson’s disease (PD) is critical for detecting early changes with the hope of better understanding the mechanisms of disease and...

  • Research Grant, 2022
    Developing a Method for Detecting Alpha-synuclein in the Acidic Cell Compartments in Which It Accumulates

    Study Rationale: The protein alpha-synuclein forms harmful clusters or aggregates that can kill neurons in the brains of people with Parkinson’s disease (PD). Neurons attempt to eliminate these clumps...

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