The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Parkinson’s Disease Therapeutics Pipeline Program, 2025Neuroprotective Therapy for PD Using Stabilizers of the LRRK2:14-3-3 Interaction, Supplement
Study Rationale: Our previous work shows that regulation of the phosphorylation of the Parkinson’s disease protein ‘leucine-rich repeat kinase 2’ (LRRK2) is a key mechanism controlling LRRK2...
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ASAP CRN Competitive Renewal Opportunity, 2025Senescence in Parkinson’s Disease and Related Disorders
Study Rationale: While aging is the greatest risk factor for development of Parkinson’s disease (PD), how aging promotes PD is not fully understood. Examining the role of cellular senescence, a major...
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MRI Biomarkers Program, 2025Molecular MRI Correlates of Parkinsonian Neurodegeneration
Study Rationale: New imaging tools for Parkinson’s disease (PD) are urgently needed to help accelerate the development of new treatments. A special type of MRI scan, CEST MRI, can detect changes in...
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Biomarkers to Support Therapeutic Trials Program, 2025Ultra-sensitive Quantification of Phosphorylated LRRK2 in Biofluids from Clinical Trials of Therapeutic Candidates
Study Rationale: LRRK2 is a protein for which inappropriate activation is associated with Parkinson’s disease (PD). Investigators are therefore pursuing the activity of LRRK2 as a potential...
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Research Grant, 2025Developing an ELISA Immunoassay for Monitoring Phosphorylation of Proteins Associated with Parkinson’s Disease
Study Rationale: As Parkinson’s disease (PD) progresses, one of the molecular changes that occurs is an increase in the number of phosphate groups that are added to proteins. In this project, we will...
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Research Grant, 2025Assessment of Artificial Intelligence (AI) and Blood-Brain Barrier Technology
Study Rationale: Companies are currently using artificial intelligence (AI) to design and develop new drugs and developing new ways to get drugs across the protective blood-brain barrier (BBB) and...
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Our funding programs support basic, translational and clinical research from academia and industry.