The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Computational Science, 2018Brain-inspired Computer Analysis of Complex Parkinson's Disease Data
Study Rationale:
Clinical research as well as wearable devices and phone apps used by people with Parkinson's disease (PD) generate large volumes of data, such as genetic and imaging data and data on... -
Target Advancement Program, 2018Hexosaminidase as a Therapeutic Target for Parkinson's Disease
Study Rationale:
Hexosaminidase (HEX) is a protein that is stored inside lysosomes, tiny bubbles inside the cell responsible for getting rid of its waste. A lack of HEX is associated with Sandhoff... -
Research Grant, 2018Registry for the Advancement of Deep Brain Stimulation Therapy in Parkinson's Disease
Study Rationale:
Deep brain stimulation (DBS) is a surgical therapy that delivers small electrical pulses to the brain to decrease movement symptoms of Parkinson's disease (PD). Registry for the... -
Improved Biomarkers and Clinical Outcome Measures, 2018Developing a Test for Circular RNA, a Possible Biomarker of Parkinson's Disease
Study Rationale:
Circular RNA (circRNA) is a recently discovered type of RNA, a molecule that plays an important role in protein production. CircRNAs are abundant in the brain and builds up when... -
Target Advancement Program, 2018Evaluating the Role and Therapeutic Potential of Natural Killer Cells in Parkinson's Disease
Study Rationale:
Natural killer (NK) cells are immune cells that defend the body against external and internal threats. While the number of NK cells is increased in Parkinson's disease (PD), it... -
Therapeutic Pipeline Program, 2018Exosomal Delivery of shRNA Minicircles to Halt Neurodegeneration and Parkinson's
Study Rationale:
Gene therapy is one of the most promising tools for the treatment of Parkinson's disease (PD). We have developed a novel system to treat brain diseases using exosomes, which are small...
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Our funding programs support basic, translational and clinical research from academia and industry.