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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2014
    Role of Parkin and Its Opponent in Parkinson’s Disease Onset

    Study Rationale:       
    Parkin is an enzyme that adds molecules to proteins, including one called mitofusin, which bridges mitochondria (cell’s powerhouse) to the endoplasmic reticulum (structure...

  • Research Grant, 2014
    Validation of the Movement Disorders Society’s Clinical Criteria of Parkinson’s Disease

    Study Rationale:
    Diagnosis of Parkinson’s disease (PD) and other causes of parkinsonism is not always an easy task for physicians. An accurate diagnosis, however, is an essential aspect of care for...

  • Therapeutic Pipeline Program, 2014
    Restoring the Nigrostriatal Pathway with Living Micro-Tissue Engineered Axonal Tracts

    Study Rationale:                   
    By the time Parkinson’s disease (PD) symptoms appear, typically 60% of neurons in the substantia nigra and their axonal projections (nerve fibers) to the striatum...

  • Rapid Response Innovation Awards, 2014
    Novel Mechanism for Death of Dopaminergic Neurons in a Model for Parkinson’s Disease

    Study Rationale:                   
    Parkinson’s disease (PD) is due in large part to the death of dopaminergic neurons in a part of the brain called the substantia nigra. An understanding of why, as we...

  • Research Grant, 2014
    Novel Nicotinic Receptor Agonist for Treating Levodopa-induced Dyskinesia

    Promising Outcomes of Original Grant:
    Our initial hypothesis was two-fold: first, that specific nicotinic (chemical messenger) receptor subtypes are involved in nervous system responses to levodopa and...

  • Research Grant, 2013
    Utility of a Novel Nicotinic Receptor Agonist for Treating Levodopa-induced Dyskinesia

    Objective/Rationale:
    It has been suggested that a nicotinic acetylcholine receptor (nAChR) agonists may restore the deficits caused by the loss of nicotinic acetylcholine subunits found in Parkinson’s...

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Our funding programs support basic, translational and clinical research from academia and industry.

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