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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2013
    Validation of Blood-borne Autoantibody Biomarkers for Parkinson’s Disease Supplement

    Promising Outcomes of Original Grant:
    The purpose of the original study was to determine if a small group of selected blood-borne autoantibody biomarkers that were previously shown to be effective in...

  • Research Grant, 2013
    Six-month Oral Toxicity Study of the Accordion Pill™ of Carbidopa/Levodopa

    Objective/Rationale:
    The Accordion Pill™ is designated to significantly stabilize the pharmacokinetic profile of drugs with a narrow absorption window, such as levodopa. Regular controlled-release...

  • Rapid Response Innovation Awards, 2013
    Transcranial Direct Current Stimulation for the Treatment of Parkinson’s Disease

    Objective/Rationale:
    Current treatments for Parkinson’s disease (PD) are either associated with side effects, expensive, or their efficacy diminishes over time. Thus, the development of practical...

  • MJFF Research Grant, 2013
    A New Tool for CSF-Based Parkinson Disease Diagnostics: Super-Resolution Microscopy Investigation of Alpha-Synuclein Aggregates

    Objective/Rationale:             
    It is still difficult to diagnose Parkinson’s Disease (PD) patients through routine assays. Clinical research on PD suggests that the aggregation (clumping) of the...

  • Target Validation, 2013
    Validation of the Transcriptional Repressor Bach1 as a Novel Target to Enhance Antioxidant Response Pathway and Block Neurodegeneration in Parkinson’s Disease

    Objective/Rationale:             
    Bach1 is a transcriptional repressor, which is a protein that binds to a specific DNA site and prevents transcription of nearby genes. Bach1 is primarily localized to...

  • RRIA (Rapid Response Innovation Awards), 2013
    Proof-of-concept Study for the Development of Non-invasive Immunotherapy for Parkinson’s Disease: Intranasal Targeting of Immunoglobulin G Antibodies and Fragments to the CNS

    Objective/Rationale:             
    Immunotherapy using antibodies directed against alpha-synuclein is an extraordinarily promising, potentially disease-modifying treatment approach for Parkinson’s...

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Our funding programs support basic, translational and clinical research from academia and industry.

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