The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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MJFF Research Grant, 2013Validation and Characterization of Exosomal Alpha-synuclein as a Diagnostic Marker for Parkinson’s Disease
Parkinson’s disease (PD) is characterized by aggregation of the intracellular alpha-synuclein protein and subsequent neurodegeneration. Recent findings suggest that extracellular alpha-synuclein forms...
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Research Grant, 2013Ubiquitous, Inexpensive Non-invasive Technologies for Objective Detection and Monitoring of Parkinson’s Symptoms
Objective/Rationale:
For doctors to diagnose and treat Parkinson’s, they need reliable tests. Unfortunately, testing the symptoms of Parkinson’s at a specialist’s office/clinic is expensive and time... -
Research Grant, 2013Prion-like Dissemination of Synuclein Pathology: A Non-human Study
Objective/Rationale:
Parkinson’s disease (PD) is characterized by the loss of midbrain dopaminergic neurons and the presence of aggregates named Lewy bodies. This pathology is believed to drive the... -
Research Grant, 2013Mu Opioid Receptor Target for Levodopa-Induced Dyskinesia: Stop or Continue? (MOR4LID)
Objective/Rationale:
The mu opioid receptor (MOR) has long been proposed as an appealing target for managing levodopa-induced dyskinesia and therefore received attention from industry, which developed... -
Target Validation, 2013PARK14: Validation of a New Pre-clinical Model of Age-dependent PD
Objective/Rationale:
The gene PARK 14 (PLA2g6) is expressed in human brain, and numerous mutations in this gene were found to be associated with PD, but the mechanism of such association is... -
Research Grant, 2013Native Alpha-Synuclein Oligomers in Living Cells: Relevance for Diagnosing and Treating Parkinson’s Disease
Objective/Rationale:
Aggregation of the protein called alpha-synuclein in nerve cells produces the hallmark pathology (Lewy bodies) of Parkinson´s disease (PD). The pathological events...
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Our funding programs support basic, translational and clinical research from academia and industry.