The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Target Validation, 2014Transferrin Receptor 2 as a Target to Halt Iron Overload in Parkinson's Disease
Objective/Rationale:
Iron is an element naturally present in the brain and is required for its proper function. Iron levels, however, must be tightly controlled because excessive amounts... -
Research Grant, 2014Phase IIb Study of Intranasal Glutathione in Parkinson’s Disease
Study Rationale:
The loss of the antioxidant glutathione in the brain of individuals with Parkinson’s disease (PD) occurs years before the onset of motor symptoms. Glutathione has... -
Target Validation, 2014Inhibition of a Dopamine Receptor in Lymphocytes as a Treatment for Parkinson's Disease
Objective/Rationale:
Emerging evidence has shown that lymphocytes, a kind of immune system cells, play a fundamental role in the development and progression of Parkinson's diseases. Our... -
Research Grant, 2014CD163+ Macrophages as Tools for Neuroinflammatory Modulation in Parkinson’s Disease Supplement
Promising Outcomes of Original Grant:
Our fundamental hypothesis was that modulation of blood CD163+ macrophages using nanoparticles loaded with anti-inflammatory drugs could protect neurons in the... -
Linked Efforts to Accelerate Parkinson’s Solutions, 2014Alpha-Synuclein Assay Standardization LEAPS
Study Rationale:
The presence of alpha-synuclein protein in biofluids such as blood, cerebrospinal fluid and saliva has been reported by multiple scientists using a variety of analytical techniques... -
Target Validation, 2014Alpha-Galactosidase A as a Therapeutic Target for Parkinson’s Disease
Objective/Rationale:
Alpha Galactosidase A (alpha-Gal A) is an enzyme that recycles lipids in cells. Our preliminary data demonstrates alpha-Gal A deficiency in brains of Parkinson’s...
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Our funding programs support basic, translational and clinical research from academia and industry.