The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Target Advancement Program, 2018Studying GLP1 Receptor as a Therapeutic Target in Parkinson's Disease
Study Rationale:
Drugs called GLP1 agonists for their ability to activate protein GLP1 receptor were originally developed to treat type 2 diabetes mellitus. However, they can travel to the brain and... -
Alpha-Synuclein Biology, 2018Using Powerful Metabolomic Methods to Identify Blood-based Biomarkers of Early-Stage Parkinson's Disease
Study Rationale:
Metabolomics is an approach to studying molecules that are products of metabolism. Using metabolomics, we identified a unique feature -- metabolic fingerprint -- in the blood of pre... -
Research Grant, 2018A Global Database of People with Inherited Parkinson's Disease
Study Rationale:
Changes (mutations) in genes PRKN, PINK1, DJ1, SNCA, LRRK2 and VPS35 can cause inherited Parkinson's disease (PD). Also, mutations in the GBA gene are associated with an increased... -
Access to Data and Biospecimens, 2018Studying Methylation in the PPMI Cohort to Develop New Biomarkers
Study Rationale:
Because Parkinson's disease (PD) is a complex disease, it is difficult to accurately diagnose and treat. Biomarkers -- disease indicators that are critical missing links in the search... -
Research Grant, 2018The Role of LRRK2 Activity in Inherited Parkinson's Disease
Promising Outcomes of Original Grant:
Mutations (changes) in the LRRK2 gene are a leading genetic cause of Parkinson's disease (PD). Previously, we sought to evaluate the connection between a common PD... -
Improved Biomarkers and Clinical Outcome Measures, 2018A Tool for Evaluating Facial Expression for Early Diagnosis of Parkinson's Disease
Study Rationale:
The hypomimia -- decreased facial expression with reduced blinking -- is a major motor sign of Parkinson's disease (PD). This clinical sign indicates movement dysfunction early in the...
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Our funding programs support basic, translational and clinical research from academia and industry.