The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Research Grant, 2017Making Changes in the Parkin Gene to Activate the Protein Parkin
Study Rationale:
The protein Parkin prevents cell death by breaking down damaged mitochondria, cells' energy generators. Mutations in the Parkin gene -- genetic changes that render the protein unable... -
Research Grant, 2017Stem Cells with Different Amounts of Alpha-synuclein as a Drug Discovery Tool
Promising Outcomes of Original Grant:
Stem cells are a renewable source of tissue that can be coaxed to become different cell types of the body. When prompted, stem cell models can become neural cells... -
Improved Biomarkers and Clinical Outcome Measures, 2017Predicting the Risk of Parkinson’s Disease with a Mathematical Formula
Study Rationale:
Currently, there is no way to predict whether a person will develop Parkinson's disease (PD) and, if so, when. We have created a mathematical formula for calculating a person's risk... -
Computational Science, 2017Analyzing Data from the Parkinson’s Progression Markers Initiative to Identify Subtypes of Parkinson’s Disease
Study Rationale:
Parkinson's disease (PD) presents and progresses variably, so no two people with Parkinson's have the same disease. The diversity of PD clinical manifestations makes the disease more... -
Computational Science, 2017Complex Data Analysis for the Development of Parkinson’s Disease Biomarkers
Study Design:
To test this hypothesis, we will employ recent discoveries in computer science, PD biomarker research and standardized sets of PD data. First, we will develop machine-learning techniques... -
Therapeutic Pipeline Program, 2017Alternative Brain Stimulation Approach for the Treatment of Swallowing Impairment in Parkinson’s Disease
Study Rationale:
Dysphagia -- difficulty swallowing -- is common in people with advanced Parkinson's disease (PD). Dysphagia often leads to aspiration -- inhaling of food -- which can result in...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.