The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Research Grant, 2017Microbiome Biomarkers for Early-stage Detection and Stratification of Parkinson's Disease
Study Rationale:
Parkinson's disease (PD) research benefits from knowledge of disease-specific risk and resilience factors and elucidation of pathophysiological concepts on the emergence of... -
Research Grant, 2017Study of a Molecule to Prevent Alpha-Synuclein Clumping and Treat Parkinson's Disease
Promising Outcomes of Original Grant:
Alpha-synuclein is a sticky protein that clumps in the brains of people with Parkinson's disease (PD). In our first project funded by The Michael J. Fox Foundation... -
LRRK2 Therapeutic and Safety Initiative, 2017Efficacy and Safety of Chronic Treatment with LRRK2 Inhibitors
Study Rationale:
LRRK2 inhibitors are among the most promising in the current generation of potential novel treatments for Parkinson's disease (PD). In pre-clinical models, long-term treatment with... -
Research Grant, 2017Studying the Parkin Protein in New Pre-Clinical Models
Promising Outcomes of Original Grant:
Mitophagy is a cellular process during which damaged mitochondria, or energy generators, are broken down. Mitophagy has been suspected to malfunction in Parkinson... -
Research Grant, 2017Drawing on the Parkinson's Progression Markers Initiative (PPMI) Data to Link Changes in the PINK1/Parkin Genes with Parkinson's Disease
Study Rationale:
Two proteins, PINK1 and Parkin, prevent cell death by breaking down damaged mitochondria, cell's energy generators. This process is known as mitophagy. Mutations in PINK1/Parkin genes... -
LRRK2 Biology Consortium, 2017Study of How LRRK2 Mutations Affect Cellular Processes that Could Lead to PD
Study Rationale:
One of the most common inherited causes of Parkinson's disease (PD) is defect in the LRRK2 protein caused by changes, or mutations, of the LRRK2 gene. LRRK2 regulates the movement of...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.