The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2017Inflammatory Parkinson's Clinical Biomarker Profiling
Study Rationale:
This study aims to compare the immune system of Parkinson's disease (PD) patients and their caregivers in an effort to determine differences between these groups. Several recently... -
LRRK2 Biology Consortium, 2017The Role of Variations in the LRRK2 Gene in Parkinson's Disease
Study Rationale:
Genes can influence one's chance of developing Parkinson's disease (PD), but it's not entirely clear how. In this study, we will use cells from people with Parkinson's to test how the... -
Access to Data and Biospecimens, 2017LRRK2 in predicting Parkinson disease risk and progression in LRRK2 mutation carriers
Study Rationale:
The G2019S mutation in the LRRK2 gene is responsible for thousands Parkinson disease (PD) cases. But, not all of the mutation carriers will develop PD. Currently, clinicians...
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LRRK2 Biology Consortium, 2017Identification of Network, Activity and Behavioral Signatures of LRRK2 Expression
Promising Outcomes of Original Grant:
Our original project investigated how the LRRK2 mutation, the principal genetic cause of Parkinson's disease (PD), alters brain activity involved in movement... -
Research Grant, 2016Investigation of the Role of PINK1-dependent Phosphorylation of Rab GTPases in Parkinson’s Disease
Study Rationale:
Mutations in the PINK1 gene lead to Parkinson’s disease. PINK1 belongs to a special class of enzymes known as protein kinases. We recently found that PINK1 targets a family of enzymes... -
Priority Target Award, 2016Advancing PINK1 Knockout Models of Parkinson’s
Study Rationale:
Loss-of-function mutations in PINK1 are causally linked to early-onset Parkinson’s disease (PD). MJFF funded the generation and initial characterization of PINK1 knockout (KO) models...
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Our funding programs support basic, translational and clinical research from academia and industry.