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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2014
    Clinical and Neuroimaging Predictors of Cognitive Decline in Parkinson’s Disease

    Objective/Rationale:
    Parkinson’s disease (PD) dementia is often preceded by a phase of mild cognitive impairment (PD-MCI), for which diagnostic criteria have been recently proposed. However, there...

  • Access to Data and Biospecimens, 2014
    CRP40 Expression as a Biomarker of Parkinson’s Disease

    Objective/Rationale:            
    Alterations in HSPA9 gene expression has been described in Parkinson’s disease (PD). Ongoing studies suggest the expression of CRP40, a gene product of HSPA9, in the...

  • Access to Data and Biospecimens, 2014
    Diffusion Tensor-based Biomarker for Parkinson's Disease

    Objective/Rationale:             
    Magnetic resonance imaging (MRI) is a common tool used to diagnose or evaluate brain diseases such as Parkinson’s disease. Typically, MRI images are read by a...

  • Rapid Response Innovation Awards, 2014
    Inhibition of Striatal-Enriched Phosphatase (STEP) to Improve Parkinson-Related Cognitive Dysfunction

    Study Rationale:                   
    As the enzyme striatal-enriched phosphatase (STEP) may be abnormally elevated in aged parkinsonian pre-clinical models with cognitive deficits, the possibility...

  • Therapeutic Pipeline Program, 2014
    Disease-modifying Chemical Probes to Inhibit Alpha-synuclein Aggregation

    Objective/Rationale:             
    There is a great need to discover novel therapeutic targets and strategies that halt or reverse the progression of Parkinson’s disease (PD). In this study we hope to...

  • Repositioning Drugs for PD, 2014
    DPP-4 Inhibitors for the Treatment of Parkinson’s Disease (Supplement)

    Promising Outcomes of Original Grant:
    Dipeptidyl protease-4 (DPP-4) inhibitors are widely used in the effective treatment of type 2 diabetes to safely regulate blood glucose levels. DPP-4 is the key...

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Our funding programs support basic, translational and clinical research from academia and industry.

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