The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Improved Biomarkers and Clinical Outcome Measures, 2017Using Automatic Acoustic Speech Analysis and REM Sleep Behavior Disorder to Detect Individuals at High Risk of Parkinson's Disease and Other Alpha-synucleinopathies
Study Rationale:
Speech is an important indicator of motor function and movement coordination and can be extremely sensitive to the progression of neurologic diseases. The aim of this project is to... -
Oligomeric & pS129 Assay LEAPS, 2017Quantification of S129 Phosphorylated Alpha-synuclein Using the AlphaLISA® Immunoassay Platform
Study Rationale:
The alpha-synuclein protein is a key player in Parkinson’s disease (PD). Our ability to understand how this protein impacts the health of neurons in the brain is directly related to... -
Improved Biomarkers and Clinical Outcome Measures, 2017Developing Biosignatures of Parkinson's Disease Using Sense of Smell
Study Rationale:
Recent reports of "super-smelling powers" published in The Lancet Neurology has triggered the idea of a specific "musky" scent in the sebum, an oily skin secretion, of those with... -
LRRK2 Biology Consortium, 2017Kinase Activity-mediated Changes in LRRK2-Parkinson's and Sporadic Parkinson's Cells and Rab Protein Function
Promising Outcomes of Original Grant:
Our previous studies have demonstrated deficits in cohesion, positioning, and polarity (important characteristics of cells that help regulate function) in... -
Research Grant, 2017Inflammation in Parkinson's Disease
Study Rationale:
The contribution of inflammation to Parkinson's disease (PD) is increasingly being recognized. However, the stage of the disease in which inflammation is prevalent and/or important...
-
LRRK2 Biology Consortium, 2017Development of Nanobodies as Novel Tools to Characterize LRRK2 as a Potential Drug Target for Parkinson's Disease
Study Rationale:
Several genes play a crucial role in Parkinson's disease (PD). The most common genetic cause of PD is mutations in the gene encoding LRRK2, a very large and complex protein with...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.