The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Parkin Therapeutic Development, 2014Pharmacological Modulation of Parkin Expression and Function to Attenuate Mitochondrial Dysfunction
Objective/Rationale:
This project aims to identify drug-like molecules that increase the amount of the protein parkin in neuronal cells. Parkin is mutated in some people with Parkinson’s disease (PD)... -
Rapid Response Innovation Awards, 2014Regulation of Alpha-synucleinopathy by BPOZ-2
Objective/Rationale:
BPOZ-2 is an anti-tumor protein that has been reported to stimulate the removal of cancer- related protein aggregates in cancer cells. However, its role has never been... -
Rapid Response Innovation Awards, 2014siRNA Screen of Microglia to Identify Neuroprotective Drug Targets in Parkinson´s Disease
Objective/Rationale:
Neuroinflammation is a fundamental process contributing to the death of neurons in Parkinson´s disease (PD). During this process, inflammatory microglia, which are the... -
Rapid Response Innovation Awards, 2014Mirtazapine as a Treatment for Pathological Gambling
Objective/Rationale:
Pramipexole (Mirapex®) is a drug that is effective at alleviating movement deficits associated with Parkinson’s disease. However, pramipexole can induce compulsive... -
Rapid Response Innovation Awards, 2014Pum2-mediated Translational Regulation of Alpha-synuclein mRNA Associated with Mitochondria
Objective/Rationale:
Aggregation of the protein alpha-synuclein and dysfunction of mitochondria (the powerhouse of the cell) are two critical components of Parkinson’s disease. We have... -
Research Grant, 2014Bioenergetic and Proteomic Profiling of PINK1, DJ-1 and Parkin Models
Objective/Rationale:
Some forms of familial Parkinson’s disease (PD) are due to mutations in the genes that code for the proteins PINK1, DJ-1 and parkin. These proteins have specific roles in the...
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Our funding programs support basic, translational and clinical research from academia and industry.