The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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GBA Biology and Therapies, 2018Molecular Imaging and Computer Typing in GBA-PD and Asymptomatic GBA-mutation Carriers
Study Rationale:
People who have a mutation in the GBA gene have a higher risk of developing Parkinson’s disease (PD) and, if they have PD, are more likely to have cognitive decline and dementia... -
LRRK2 LEAPS, 2018Link between LRRK2, Alpha-synuclein and Lysosomal Function Supplement
Study Rationale:
Our goal is to test whether people with Parkinson’s disease (PD) who carry a LRRK2 mutation (compared to those carrying another genetic PD-predisposing mutation or people with... -
Therapeutic Pipeline Program, 2018Discovery and Development of Novel Parkin Activators
Study Rationale:
Parkinson's disease is characterized by a loss of nerve cells (neurons) in the brain resulting potentially from their inability to remove damaged mitochondria, which control energy... -
Research Grant, 2018Developing Biosignatures of Parkinson's Disease Using Sense of Smell Supplement
Promising Outcomes of Original Grant:
Recent reports of people with “super-smelling powers” have triggered the idea that there exists a specific scent in Parkinson’s patients’ sebum, an oily skin... -
Target Advancement Program, 2018Evaluation of PARIS ASOs in Models of Parkinson's Disease
Study Rationale:
The parkin-interacting substrate (PARIS) prevents genes that are important in the survival of dopamine neurons from working by limiting their expression in neurons. Previously we... -
Therapeutic Pipeline Program, 2018Bitopertin to Alleviate Dyskinesia in Parkinson's Disease
Study Rationale:
Levodopa-induced dyskinesia is abnormal involuntary movements that can affect people with Parkinson's disease after years of treatment. Available therapies for dyskinesia are only...
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Our funding programs support basic, translational and clinical research from academia and industry.