The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Target Advancement Program, 2016Targeting the Mitochondrial Unfolded Protein Response in Alpha-synuclein-induced Parkinson's Disease
Study Rationale:
The mitochondrial (powerhouse of the cell) unfolded protein response (mtUPR) is the first defense mechanism for maintaining proper quality of proteins within the mitochondria. Defects... -
Research Grant, 2016Novel Quantification in Parkinson’s Disease Neurochemical Imaging
Promising Outcomes of Original Grant:
We hypothesized in the original funded grant that evaluation of texture and variability, beyond conventional averaging of voxel (element of space) intensities... -
Target Advancement Program, 2016Farnesoid X Receptor as a Target to Reduce Meuroinflammation
Study Rationale:
Although the precise mechanism(s) of neurodegeneration in Parkinson's disease (PD) are unknown, evidence suggests that neuroinflammation is an important contributor. In this study, we... -
Research Grant, 2016The Determinants and Functional Consequences of LRRK2 Dimer Formation
Study Rationale:
The protein LRRK2 has a strong tendency to self-associate in pairs, which plays an important role in how it functions in cells. Mutations in LRRK2 that cause a type of Parkinson's...
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Target Advancement Program, 2016Neuroprotective Effects of Endosulfine-alpha in PD
Study Rationale:
Evidence suggests that alpha-synuclein can cause cell death in the brains of those with Parkinson's disease (PD) by forming clusters (or aggregates) on the surface of small storage... -
Research Grant, 2016LRRK2 Non-coding Variation in Parkinson's Disease
Study Rationale:
Genetic studies looking at differences in DNA have identified key genes that can cause Parkinson's disease (PD) in families and contribute to the overall risk of developing sporadic...
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Our funding programs support basic, translational and clinical research from academia and industry.