The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Access to Data & Biospecimens, 2015Whole Genome Sequencing and Analysis of the PPMI Prodromal and Genetic Cohorts, PPMI Genetic Registry and the LRRK2 Cohort Consortium
Study Rationale:
This work aims to provide genetic information for the whole genome and assess the role of the identified genetic information in Parkinson disease. To do this...
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Access to Data & Biospecimens, 2015Evaluation of Alpha-synuclein and Hemoglobin Levels in CSF, Plasma and Saliva samples from the BioFind Cohort
Study Rationale:
Alpha-synuclein pathology plays a major role in Parkinson’s disease (PD). Recent studies suggest that measurement of alpha-synuclein in biological fluids (e.g...
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Research Grant, 2014Development of an MgluR4 PET Radioligand
Study Rationale:
mGluR4 is a glutamate receptor that is believed to be a potential therapeutic target for Parkinson’s disease (PD). Developing an imaging tracer may allow researchers... -
Rapid Response Innovation Awards, 2014Improving Gait in Parkinson’s Disease Patients by Non-invasive Electrical Stimulation of the Cerebellum
Study Rationale:
People with Parkinson’s disease (PD) can experience difficulties walking (e.g., freezing), which can lead to falls and negatively impact quality of life. These symptoms are difficult... -
Improved Neuromodulation Approaches, 2014Adaptive Closed Loop Neuromodulation and Neural Signatures of Parkinson’s Disease
Study Rationale:
Currently deep brain stimulation (DBS) is limited to “open-loop” stimulation, without real-time adjustment to the patient’s state of activity, fluctuations and types of motor symptoms... -
Rapid Response Innovation Awards, 2014Creating Dopaminergic Neurons in the Adult Brain
Study Rationale:
Loss of dopaminergic neurons is seen in Parkinson’s disease, and transplantation of these neurons can greatly ease symptoms. However, several major drawbacks are associated with...
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Our funding programs support basic, translational and clinical research from academia and industry.