The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Access to Data and Biospecimens, 2014Analysis of Brain and Peripheral Small Molecule Levels in Parkinson’s Disease
Study Rationale:
Parkinson’s disease is accompanied by a loss of chemical signaling molecules in the brain and body. For instance, chemicals like dopamine are lost in both the gut and in the brain... -
Rapid Response Innovation Awards, 2014Exploration of Relationships and Formulations of Molecular Tweezers
Study Rationale:
A key mechanism leading to death of neurons in the brain is formation of toxic clumps of the protein alpha-synuclein. Therefore blocking the formation of these toxic... -
Access to Data and Biospecimens, 2014Verification of a Long, Non-coding RNA in Blood as a Biomarker for Parkinson's Disease
Study Rationale:
We have discovered a long, non-coding RNA (RNA that does not encode a protein) that shows a five-fold decrease within the brains of people with Parkinson’s disease (PD) compared... -
Therapeutic Pipeline Program, 2014TDO Inhibitors: A New Treatment Option for Parkinson’s Disease
Study Rationale:
Tryptophan-2,3-dioxygenase (TDO) is a key enzyme in the tryptophan degradation pathway. In a Parkinson’s disease (PD) model, TDO was identified as a potential... -
Research Grant, 2014PARK14-dependent SOCE and Sporadic Parkinson’s Disease
Objective/Rationale:
Mutations in the PARK14 gene are associated with Parkinson’s disease (PD), but its role in idiopathic PD is presently unknown. Recently we identified a role of PARK14... -
Target Validation, 2014Melanoma-related Gene as a Therapeutic Target for Parkinson's Disease
Objective/Rationale:
Individuals with Parkinson’s disease (PD) are more likely to develop melanoma. Conversely, melanoma patients are at higher risk of developing PD. This bidirectional link...
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Our funding programs support basic, translational and clinical research from academia and industry.