The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant Supplement, 2014GluN2D Antagonism in the Subthalamic Nucleus for the Treatment of Parkinsonism
Promising Outcomes of Original Grant:
The goal of the original grant was to identify new chemical compounds that block specific types of receptors for the neurotransmitter glutamate and test whether... -
Rapid Response Innovation Awards, 2014Motor Proteins as Novel Drug Targets of Disease-modifying Treatments for Parkinson’s Disease
Objective/Rationale:
More and more research suggests that part of the cellular quality control mechanism, which degrades abnormal proteins or damaged parts of the cell, is defective in Parkinson’s... -
Research Grant, 2014Probing Nurr1 Expression in Parkinson’s Disease
Objective/Rationale:
Impaired function of the hormone receptor Nurr1 might contribute to the pathogenesis of Parkinson’s disease (PD) and is an active target for novel therapeutics. Previous studies... -
Access to Data and Biospecimens, 2014Diffusion Tensor-based Biomarker for Parkinson's Disease
Objective/Rationale:
Magnetic resonance imaging (MRI) is a common tool used to diagnose or evaluate brain diseases such as Parkinson’s disease. Typically, MRI images are read by a... -
Rapid Response Innovation Awards, 2014Inhibition of Striatal-Enriched Phosphatase (STEP) to Improve Parkinson-Related Cognitive Dysfunction
Study Rationale:
As the enzyme striatal-enriched phosphatase (STEP) may be abnormally elevated in aged parkinsonian pre-clinical models with cognitive deficits, the possibility... -
Therapeutic Pipeline Program, 2014Disease-modifying Chemical Probes to Inhibit Alpha-synuclein Aggregation
Objective/Rationale:
There is a great need to discover novel therapeutic targets and strategies that halt or reverse the progression of Parkinson’s disease (PD). In this study we hope to...
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Our funding programs support basic, translational and clinical research from academia and industry.