The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2019New Activators of Parkin
Study Rationale:
Parkin is a protein made by all cells in the body, including brain cells. It plays an important role in the protection of neurons through a process known as quality control. Changes... -
Research Grant, 2019Imaging Techniques to Evaluate LRRK2 Activity in Idiopathic Parkinson's Disease
Study Rationale:
Inherited mutations in the LRRK2 gene are a common cause of Parkinson's disease that presents with clinical symptoms and brain changes similar to idiopathic (cause unknown) Parkinson... -
Research Grant, 2019Computer Simulation of LRRK2 and GBA Interactions to Identify Therapeutic Targets for Parkinson's Disease
Promising Outcomes of Original Grant:
Our original project aimed to create a computer simulation of biological pathways involved in Parkinson's disease and how genetic mutations in LRRK2 can change... -
Research Grant, 2019Developing an Alpha-synuclein Imaging Agent
Study Rationale:
The goal of this study is to develop an imaging tool (a radiotracer) that could be used to show the protein alpha-synuclein in the brains of living people with a brain scan call a... -
Alpha-Synuclein Biology and Therapies, 2019How Does Alpha-synuclein Cause Neurodegeneration?
Study Rationale:
The protein alpha-synuclein has a central, causative role in Parkinson's disease, but we do not understand how it contributes to cell degeneration. Mutations in the gene (SNCA) that... -
Research Grant, 2019Interpretation of Accelerometer Data with Deep Learning
Study Rationale:
In-home monitoring of the severity of Parkinson's disease (PD) may help guide therapeutic decisions and prevent life-threatening falls. Deep learning is the state-of-the-art tool for...
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Our funding programs support basic, translational and clinical research from academia and industry.