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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2016
    Study of Alpha-synuclein in the Dorsal Neostriatum

    Promising Outcomes of Original Grant:
    In February 2013, Luk et al. published in Science that administration of synthetic alpha-synuclein into pre-formed fibrils in pre-clinical models was sufficient to...

  • Therapeutic Pipeline Program, 2016
    Effect of HDAC Inhibition in Models of Parkinson's Disease

    Study Rationale:
    Numerous publications have linked the family of epigenetic enzymes known as HDACs (histone deactylases) to the underlying pathology of Parkinson's. This study will test the efficacy of...

  • Therapeutic Pipeline Program, 2016
    Cognitive Behavioral Therapy for Anxiety Disorders in Parkinson's Disease

    Study Rationale:
    Anxiety disorders occur in up to 35 percent of people with Parkinson's disease and can have a negative impact on gait, involuntary movements, motor fluctuations and quality of life...

  • Therapeutic Pipeline Program, 2016
    Rehabilitation Treatment for Airway Protection in Parkinson's Disease

    Study Rationale:
    Aspiration pneumonia is a leading cause of death in persons with Parkinson's disease (PD). One of the main reasons people with PD develop aspiration pneumonia is that they often have...

  • Improved Biomarkers and Clinical Outcome Measures, 2016
    Supramolecular Hosts as Combined Protein Aggregation Inhibitors and Hyperpolarized MRI Reporters

    Study Rationale:
    Amyloid fibrils play a key role in Parkinson's disease (PD) and monitoring of their formation from self‐assembled insoluble molecular aggregates would be extremely valuable as a...

  • Research Grant, 2016
    Parkinson's Disease Genetics Sequencing Consortium

    Study Rationale:
    The Parkinson's Disease Genetics Sequencing Consortium (PDGSC) was established following a National Institute of Neurological Disorders and Stroke workshop in June 2014 and brings...

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Our funding programs support basic, translational and clinical research from academia and industry.

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