The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Parkin Biology, 2013Deciphering and Exploiting the Neuroprotective Activity of Parkin
Objective/Rationale:
Mutations in the Parkin gene are responsible for parkinsonism, and there is evidence that Parkin is inactivated in sporadic (cause unknown) Parkinson's disease... -
Research Grant, 2013Effect of NPT088 in Alpha-synuclein Overexpressing Models
Promising Outcomes of Original Grant:
NeuroPhage technology simultaneously targets multiple misfolded proteins (e.g., alpha-synuclein, amyloid-beta, phosphorylated tau) involved in neurodegenerative... -
Neurotrophic Factors Challenge, 2013Exploring a Novel Neurotrophic Factor to Protect the Nigrostriatal Dopaminergic System and Alleviate Motor Deficits
Objective/Rationale:
Safety and effectiveness in brain delivery remain two major challenges in developing novel neuroprotective agents to treat Parkinson’s disease (PD) patients. This... -
Cognition Biomarkers, 2013Insulin-like Growth Factor-1 and DAT Imaging as Biomarkers of Early Cognitive Impairment in Parkinson’s Disease
Objective/Rationale:
Evidence supports that the protein insulin-like growth factor-1 (IGF-1) may be involved in cognitive deficits. An earlier study found that low serum IGF-1 levels... -
Rapid Response Innovation Awards, 2013Novel Quantification Paradigm in Parkinson’s Disease Neurochemical Imaging
Objective/Rationale:
Parkinson’s disease imaging using dopamine transporter (DAT) single-photon emission computed tomography (SPECT) technology conveys important information on brain... -
Rapid Response Innovation Awards, 2013Novel Method for Therapeutic Gene Silencing in the Brain
Objective/Rationale:
Reducing the activity of certain genes — called gene silencing — implicated in Parkinson’s disease may be a therapeutic approach that could prevent or slow the disease...
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Our funding programs support basic, translational and clinical research from academia and industry.