The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Dyskinesia Challenge, 2012Evaluation of Cortical Resonant Oscillations as a Novel Target for Treatment of Dyskinesia
Objective/Rationale:
In our research we aim to identify changes in neuronal circuits that cause motor symptoms in Parkinson’s disease (PD) by recording neuronal activity in healthy and in... -
Rapid Response Innovation Awards, 2012Polyglutamine Repeats and Parkinson Disease
Objective/Rationale:
Trinucleotide repeat expansion is a gene mutation where the codons (the groups of DNA components that correspond to amino acids) exceed the maximum of a certain gene... -
Dyskinesia LEAPS, 2012Topiramate as an Adjunct to Amantadine in the Treatment of Dyskinesia in Parkinson's Disease
Objective/Rationale:
Dyskinesia is a term used to describe involuntary movements that develop as side effects of dopamine drugs used to treat Parkinson's disease. Dyskinesias are frequent and... -
Research Grant, 2012The Transfer of Alpha-Synuclein: Mechanistic and Therapeutic Studies
Objective/Rationale:
This three-year collaborative project between three seasoned Parkinson’s disease (PD) investigators capitalizes on their extensive PD research experience and new understanding of... -
Neurotrophic Factors Challenge, 2012Novel Cell-based Strategy for GDNF Delivery in Parkinson's Disease
Objective/Rationale:
Glial cell line-derived neurotrophic factor (GDNF) is the most potent nerve cell growth molecule capable of protecting the dopamine neurons that are affected in... -
LRRK2 in the Immune System, 2012Investigation of Neuroinflammation in LRRK2 Mutation Carriers Using Positron Emission Tomography
Objective/Rationale:
There is evidence that LRRK2 mutation may alter the immune response in such as way as to potentiate neuroinflammatory responses to external triggers, with a...
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Our funding programs support basic, translational and clinical research from academia and industry.