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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2009
    Defining Genetic Factors for PD in a Conserved Population

    Objective/Rationale
    The identification of genes underlying risk for Parkinson’s disease (PD) helps to further the understanding of this complex disorder, with the discovery of new genes contributing...

  • Program-non-specific Funding, 2009
    Data Repository for Experimental Data

    Objective/Rationale
    Synthesizing biomedical data into effective discoveries is greatly hampered by the way science is both reported in research articles and stored in databases. Articles do not...

  • Rapid Response Innovation Awards, 2009
    Development of Potent Conformation-Specific Compounds Directed to Monomeric Alpha-Synuclein

    Promising Outcomes of Original Grant:
    The goal of our original funded grant was to use our alpha-synuclein assay to identify compounds that prevent conformational change to the fully open form of the...

  • Rapid Response Innovation Awards, 2009
    Evaluation of a Viral Non-coding RNA as a Neuroprotective and Neurorestorative Therapy in Chronic Models of Parkinson's Disease

    Promising Outcomes of Original Grant:
    Previously, we asked whether a novel viral non-coding RNA (an RNA which does not appear to encode a protein), but with known pro-life functions, could act to...

  • Target Validation, 2009
    Testing PDE-1 Inhibitor in MPTP-treated Macaques

    Promising Outcomes of Original Grant:
    Our goal is to develop novel therapeutic molecules that promote normal dopamine neurotransmission in the brain affected by PD. We hypothesize that these molecules...

  • Rapid Response Innovation Awards, 2009
    Effect of novel sirtuin inhibitors on alpha-synuclein toxicity in a Parkinson disease pre-clinical model

    Objective/Rationale: 
    The objective of the proposed research is to test the ability of novel sirtuin inhibitors to protect against dopamine neuron toxicity in a pre-clinical model of Parkinson's...

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Our funding programs support basic, translational and clinical research from academia and industry.

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