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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • , 2025
    Harmonization of LRRK2 Parkinson’s Disease Cohorts

    Study Rationale: LRRK2 variants are the most common cause of autosomal dominant Parkinson’s disease yet the natural history of LRRK2 Parkinson’s disease is not fully understood. While multiple LRRK2 P...

  • Research Grant, 2025
    A Meta-Analysis of Single Nucleus Allele Specific Expression to Investigate Parkinson's Disease

    Study Rationale: We will study “allele-specific expression” to understand how DNA variants relevant to Parkinson’s disease impact the expression of genes. By looking in each cell, we can check whether...

  • Research Grant, 2025
    Identifying and Pilot Testing Best Practices for Sharing Amyloid PET Research Information with Individuals Living with Lewy Body Diseases

    Study Rationale: Biomarkers are tests that measure something about a person’s health. Research studies often include biomarkers, but research participants may or may not receive the results. This...

  • Research Grant, 2026
    Bidirectional Genome-wide CRISPRi/a Screening Using Ratiometric GCase Substrates to Identify Genetic Modulators of Lysosomal GCase Activity

    Study Rationale:  

    Mutations in the gene GBA1, are the most common genetic risk factor for Parkinson Disease (PD)Mutations in GBA1 lead to malfunctioning of the protein glucocerebrosidase, which acts...

  • Research Grant, 2026
    A Novel Digital Music-based Autonomous Personalized Walking Intervention to Improve Gait and Walking Automaticity in Parkinson Disease

    Study Rationale:

    People with Parkinson disease often take small, slow and unsteady steps, which makes it hard to get around and lowers their quality of life. While focusing on walking can help a little...

  • Research Grant, 2026
    Deciphering Intracellular Pathways Altered by LRRK2 Kinase Activity and Phospho-RAB Effector Function

    Study Rationale:                   

    Gain-of-function mutations in LRRK2 cause familial Parkinson’s disease (PD) and increase the risk of developing the sporadic form of the disease. However, how...

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