The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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LRRK2 Biology Consortium, 2017Describing the Structure and Function of LRRK2
Study Rationale:
Although leucine-rich repeat kinase 2 (LRRK2) is the greatest known genetic contributor to Parkinson's disease (PD), little is known about its structure and function. To better... -
Research Grant, 2017Using Neural Cells to Test New Drugs that Activate PINK1 and Parkin
Promising Outcomes of Original Grant:
Even though most people with Parkinson's disease (PD) do not have a genetic mutation -- a change in their DNA -- that causes the disease, genes can influence the... -
Research Grant, 2017Radioactive Molecules for Detection of Alpha-synuclein and Amyloid-beta in the Brain
Study Rationale:
We will develop radioactive alpha-synuclein and beta-amyloid tracers -- molecules that allow researchers and clinicians to detect these two proteins in the brain using imaging... -
Access to Data & Biospecimens, 2017Klotho and Parkinson’s disease
Study Rationale:
Genetic studies have identified a powerful “aging suppressor gene”, Klotho, that may play a role in delaying age-related declines in cellular and tissue functioning...
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LRRK2 Biology Consortium, 2017The Role of Variations in the LRRK2 Gene in Parkinson's Disease
Study Rationale:
Genes can influence one's chance of developing Parkinson's disease (PD), but it's not entirely clear how. In this study, we will use cells from people with Parkinson's to test how the... -
Access to Data and Biospecimens, 2017LRRK2 in predicting Parkinson disease risk and progression in LRRK2 mutation carriers
Study Rationale:
The G2019S mutation in the LRRK2 gene is responsible for thousands Parkinson disease (PD) cases. But, not all of the mutation carriers will develop PD. Currently, clinicians...
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Our funding programs support basic, translational and clinical research from academia and industry.