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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • MJFF Research Grant, 2009
    Neoangiogenesis and blood-brain barrier in L-DOPA-induced dyskinesia

    Promising Outcomes of Original Grant:
    Working on a pre-clinical model of Parkinson´s disease, we have found that levodopa treatment induces proliferation of endothelial cells and angiogenesis in the...

  • MJFF Research Grant, 2009
    Specific Inhibition of Nucleation of Alpha-Synuclein Aggregation as a Therapeutic Strategy

    The discovery of specific genes associated with rare, genetic forms of Parkinson’s disease has opened the opportunity to investigate the mechanisms of the disease and to develop novel drugs. Parkinson...

  • Understanding LRRK2 Biology, 2009
    Building a LRRK2 Cohort Core Database

    Objective/Rationale
    MJFF is funding the expansion of two international LRRK2 cohorts to gain insight into the relationship of this genetic mutation to Parkinson’s disease.  Within each funded study...

  • Postural Instability and Gait Disturbances, 2009
    Neuroanatomical Correlates of Dopamine Responsive and Non-responsive Gait and Balance Impairment in Parkinson's Disease

    Objective/Rationale:
    Parkinson’s is more than a motor disorder that responds to dopamine replacement. Dopamine non-responsive features account for much of the disability that develops with disease...

  • Postural Instability and Gait Disturbances, 2009
    Relationship between REM Behavior Disorder and Freezing of Gait in Parkinson's Disease

    Objective/Rationale:
    Many people with REM sleep behavior disorder (RBD), a disease associated with disturbance of sleep, eventually develop Parkinson’s disease. Dysfunction and degeneration of...

  • Postural Instability and Gait Disturbances, 2009
    Determining the Neural Correlates of Freezing of Gait in Parkinson's Disease Using Functional Magnetic Resonance Imaging

    Objective/Rationale:
    Freezing of Gait (FOG) in Parkinson’s disease occurs when a person’s feet become suddenly ‘frozen’ while walking or turning. FOG is a leading cause of falls, and responds poorly to...

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Our funding programs support basic, translational and clinical research from academia and industry.

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