The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2019Supplement: Investigation of PINK1-dependent Phosphorylation of Rab GTPases
Promising Outcomes of Original Grant:
We were trying to understand how the PINK1 gene targets a set of proteins known as Rab GTPases through protein modification known as phosphorylation. The... -
Improved Biomarkers and Clinical Outcome Measures, 2019Applying Artificial Intelligence for Early Identification of Parkinson’s Disease
Study Rationale:
The nervous system regulates heart rate in response to situations such as stress and emergencies. Dysfunction of part of the nervous system controlling the heart can cause changes in... -
Priority Target Award, 2016Advancing PINK1 Knockout Models of Parkinson’s
Study Rationale:
Loss-of-function mutations in PINK1 are causally linked to early-onset Parkinson’s disease (PD). MJFF funded the generation and initial characterization of PINK1 knockout (KO) models... -
Research Grant, 2019Immune Cell Dysfunction in PINK1 Parkinson’s Models
Promising Outcomes of Original Grant:
In our previous project, we significantly advanced the characterization of PINK1 knockout (KO) models. We found evidence of innate and adaptive immune cell... -
Research Grant, 2019PPM1H Activators for the Treatment of Parkinson’s Disease
Study Rationale:
Although Parkinson’s disease (PD) causes are in most cases unknown (idiopathic) some cases are linked to a person’s genetics. Leucine-rich repeat kinase 2 (LRRK2) is a very important... -
Research Grant, 2019Enhancing the Clinical Utility of Data-Driven Parkinson’s Subtypes with Knowledge Distillation and Visualization
Study Rationale:
Data-driven analytics, such as machine learning methods, have been applied to discover comprehensive Parkinson’s disease (PD) subtypes from observational patient data. However, many...
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Our funding programs support basic, translational and clinical research from academia and industry.