Thomas Durcan is an associate professor at the Montreal Neurological Institute (The Neuro) and director of The Neuro’s Early Drug Discovery Unit. His research focuses on understanding the cell biology behind neurological disorders, including Parkinson’s disease (PD). His group at The Neuro uses the genome-editing tool CRISPR to develop imaging-based assays in brain cells derived from stem cells to advance our understanding of the causes of PD, amyotrophic lateral sclerosis (ALS) and neurodevelopmental disorders. His overall goal is to better understand why these diseases occur, while applying this insight towards the development of a translational program with industry partners to accelerate access to novel and next generation therapies for individuals living with neurodegenerative disorders. His research is supported by a range of funders, including Brain Canada, the Canadian Institutes of Health Research, CFREF/Healthy Brains for Healthy Lives, The Michael J. Fox foundation, Parkinson’s Canada and the U.S. Department of Defense.
Associated Grants
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Use of a Stem-cell-based Platform to Screen for Environmental Factors in Parkinson’s Disease
2024
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Using A Screening Platform Based on Induced-pluripotent Stem Cells to Study Parkinson’s Disease
2024
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Generation of Induced Pluripotent Stem Cells with Indigenous Ancestry to Promote Inclusion of North America’s First Peoples in Parkinson’s Disease Research
2024