The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Therapeutic Pipeline Program, 2021Identifying Small Molecule Binders of the LRRK2 WD Domain
Study Rationale:
Individuals with genetic variations or mutations in a gene called LRRK2 are at increased risk of developing Parkinson’s disease (PD). Because these alterations enhance the activity of... -
Therapeutic Pipeline Program, 2021Assessing the Potential of Low-Dose Carbon Monoxide Therapy in Parkinson’s Disease
Study Rationale:
Although carbon monoxide (CO) is commonly considered harmful, a growing body of research suggests that low doses of CO can stimulate physiologic processes that may protect against... -
Analysis of Patient-Reported Outcomes from Fox Insight, 2021Overcoming Underrepresentation to Improve Generalizability in Fox Insight
Study Rationale:
Fox Insight is an online clinical study that surveys over 25,000 people with Parkinson disease (PD) about their overall health, symptoms and well-being. Unfortunately, certain groups... -
Expanding Biological Understanding of PD, 2021Assessing Inhibition of NLRP3 to Reduce Brain Inflammation in Parkinson’s Disease
Study Rationale:
Recent studies indicate that brain inflammation caused by activation of a protein complex called the NLRP3 inflammasome worsens Parkinson’s disease (PD). Although multiple drugs that... -
Therapeutic Pipeline Program, 2021Using Ketamine to Treat Depression in Parkinson’s Disease
Study Rationale:
Depression affects around half of people with Parkinson’s disease (PD). However, existing antidepressants are not effective in treating these symptoms in PD and new treatments are... -
Outcome Measures, 2021Assessing Parkinson’s at Home: Contactless Monitoring of Sleep, Motor Symptom Progression and Medication Response
Study Rationale:
The ability to accurately monitor Parkinson’s disease (PD) progression and medication response at home can significantly benefit disease management and drug development. In the past...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.