The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Fall 2021 RFP: Accelerating Early Proof-of-Concept Testing of Promising PD Therapies, 2022Use of Itaconate to Improve Metabolic Regulation in Parkinson's Disease
Study Rationale: In people with Parkinson’s disease (PD), chronic inflammation and metabolic reprogramming triggers neuronal cell death. Impaired function of the proteins involved in cellular...
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Fall 2021 RFP: Expanding Biological Understanding of PD, 2022Identifying a Molecular Signature of DNA Damage in the Blood Cells of People with Parkinson’s Disease
Study Rationale: The instructions needed to govern the function of living things are stored in their cells’ DNA. In cell types that divide, such as blood or skin, DNA checked for damage and repaired...
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Fall 2021 RFP: Expanding Biological Understanding of PD, 2022Examining Fatty Acid Imbalances in Parkinson’s Disease
Study Rationale: In people with Parkinson’s disease (PD), alpha-synuclein proteins aggregate to form structures called Lewy Bodies (LBs). These LBs have recently been found to also contain lipid...
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2022: Accelerated Therapeutics Program, 2022Translation of the Neuroprotective Immune Modulator LBT-3627 into First-In-Human Studies
Study Rationale: LBT-3627 is a disease-modifying therapeutic candidate that has been shown to reduce brain inflammation and immune imbalance in preclinical models of Parkinson's disease (PD). A recent...
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Fall 2021 RFA: Promoting Diversity, Equity and Inclusion in Parkinson’s Disease Research, 2022Disparities in Neurocognitive Impairment Among Hispanics and Latinos in the United States with Parkinson’s Disease: The Role of Cardiovascular Risk
Study Rationale: In the United States, Latinos with Parkinson’s disease (PD) are more likely to have problems with memory, planning and other thinking skills than individuals of other ethnic/racial...
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Diversity, Equity and Inclusivity in Parkinson's research, 2022Identifying Barriers and Motivators Associated with Access to Care and Participation in Genetic Research Studies for Parkinson's Disease among Asian Americans
Study Rationale: Clinicians have observed that Asian Americans are older and have had symptoms for a longer period of time than Whites when they are diagnosed with Parkinson’s disease (PD). In...
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Our funding programs support basic, translational and clinical research from academia and industry.