Dr. Christian Metallo is a professor at the Salk Institute for Biological Studies. His work focuses on mapping complex metabolic processes to uncover disease-causing pathways. Using tracer molecules and advanced mass spectroscopy techniques, his lab identifies how molecules are broken down and rebuilt, where metabolites end up in the body and what regulates these processes. Taking this approach, Dr. Metallo has made key discoveries about the metabolic pathways that drive cancer progression and macular disease pathways, which can then be influenced through dietary manipulations or targeted therapies. Professor Metallo will investigate the effects of pharmacological interventions using itaconate on metabolic and inflammatory changes during Parkinson's disease.