The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2021Hypoxia (Limiting Oxygen Levels) as a Novel Treatment for Parkinson’s Disease
Study Rationale:
Many anecdotes suggest that people with Parkinson’s disease (PD) can experience a marked improvement in symptoms when they travel to the mountains or during flights at high altitude... -
Target Advancement Program, 2021Modulation of Epigenetic Regulator HDAC4 as a Parkinson’s Treatment
Study Rationale:
Scientists can take skin cells from people with Parkinson’s disease (PD), turn them into stem cells, and then engineer them into dopamine neurons, the cell type lost in PD. Our... -
Target Advancement Program, 2021Targeting the Neurovascular Unit to Prevent Dissemination and Progression of Parkinson’s Disease
Study Rationale:
The cells residing in the brain are physically separated from the blood stream by the blood-brain barrier, a specialized grouping of cells that reduces transfer from the blood... -
Target Advancement Program, 2021Use of Therapeutic Nanoparticles to Inhibit Toxic Aggregation of Alpha-Synuclein
Study Rationale:
A hallmark of Parkinson’s disease (PD) is the abnormal accumulation of clumps of alpha-synuclein in nerve cells. These improperly folded protein clumps contribute to the symptoms of... -
Therapeutic Pipeline Program, 2021Directed Evolution of Tailor-Made Molecular Chaperones
Study Rationale:
For cells to operate properly, the proteins they produce must fold properly and maintain the correct three-dimensional structure. This process relies on a special class of proteins... -
Therapeutic Pipeline Program, 2020Adaptive Deep Brain Stimulation for Gait Retraining in Parkinson's Disease
Study Rationale:
Walking impairment in people with Parkinson’s disease (PD) often arises from difficulties in coordinating leg movements in response to environment changes. Continuous stimulation of...
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Our funding programs support basic, translational and clinical research from academia and industry.