The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2018Clinicopathological Correlates in LRRK2-Related Parkinson's Disease
Promising Outcomes of Original Grant:
With previous funding from MJFF, we established the largest collection of clinically characterized autopsies from Parkinson's patients with a LRRK2 mutation, from... -
Research Grant, 2018Alpha-synuclein/Tau Imaging Consortium
Study Rationale:
Abnormal forms of alpha-synuclein and tau proteins are hallmarks of Parkinson's disease and frontotemporal dementia (FTD), respectively, and believed to be early disease indicators... -
Research Grant, 2018Exploring the Mechanisms of Neuropathology in D620N VPS35 Knockin Mice
Study Rationale:
Recent findings indicate that mutations in the VPS35 gene cause a type of familial Parkinson's disease. Normally VPS35 is involved in the trafficking of protein cargo, but we don't... -
Research Grant, 2018Functional Fine-mapping of LRRK2 Locus
Study Rationale:
Genetic studies for Parkinson's disease have indicated that variants of the LRRK2 gene are associated with increased risk of Parkinson's disease. However, we still know very little... -
Research Grant, 2018Optimization of Probe-ELISA Parkin Activity Assay
Promising Outcomes of Original Grant:
Certain forms of Parkinson's are due to defects in a cellular regulatory node known as the PINK1-Parkin pathway. With previous funding from MJFF, we sought to... -
Research Grant, 2018Evaluating the Therapeutic Potential of the Systemic Antagonism of Dopamine Receptor D3
Promising Outcomes of Original Grant:
Parkinson's disease involves toxic forms of certain proteins (e.g., alpha-synuclein) in the brain, which trigger an immune response driven by inflammatory...
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Our funding programs support basic, translational and clinical research from academia and industry.