The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2018A Global Database of People with Inherited Parkinson's Disease
Study Rationale:
Changes (mutations) in genes PRKN, PINK1, DJ1, SNCA, LRRK2 and VPS35 can cause inherited Parkinson's disease (PD). Also, mutations in the GBA gene are associated with an increased... -
Access to Data and Biospecimens, 2018Studying Methylation in the PPMI Cohort to Develop New Biomarkers
Study Rationale:
Because Parkinson's disease (PD) is a complex disease, it is difficult to accurately diagnose and treat. Biomarkers -- disease indicators that are critical missing links in the search... -
Research Grant, 2018The Role of LRRK2 Activity in Inherited Parkinson's Disease
Promising Outcomes of Original Grant:
Mutations (changes) in the LRRK2 gene are a leading genetic cause of Parkinson's disease (PD). Previously, we sought to evaluate the connection between a common PD... -
Improved Biomarkers and Clinical Outcome Measures, 2018A Tool for Evaluating Facial Expression for Early Diagnosis of Parkinson's Disease
Study Rationale:
The hypomimia -- decreased facial expression with reduced blinking -- is a major motor sign of Parkinson's disease (PD). This clinical sign indicates movement dysfunction early in the... -
Research Grant, 2018New Imaging Agents for Parkinson's Disease and Related Disorders
Study Rationale:
Imaging is a powerful tool that can be used to visualize the structure and function of the brain in living subjects. In this study, we aim to develop a new brain imaging chemical... -
Research Grant, 2018Purine Biomarkers of LRRK2-Associated Parkinson's Disease
Objective/Rationale:
Oxidative damage to brain cells - akin to rust on car parts - builds up in Parkinson's disease (PD) and leads to breakdown of brain functions. Urate is a natural antioxidant that...
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Our funding programs support basic, translational and clinical research from academia and industry.