The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Target Advancement Program, 2016Farnesoid X Receptor as a Target to Reduce Meuroinflammation
Study Rationale:
Although the precise mechanism(s) of neurodegeneration in Parkinson's disease (PD) are unknown, evidence suggests that neuroinflammation is an important contributor. In this study, we... -
Research Grant, 2016The Determinants and Functional Consequences of LRRK2 Dimer Formation
Study Rationale:
The protein LRRK2 has a strong tendency to self-associate in pairs, which plays an important role in how it functions in cells. Mutations in LRRK2 that cause a type of Parkinson's...
-
Target Advancement Program, 2016Neuroprotective Effects of Endosulfine-alpha in PD
Study Rationale:
Evidence suggests that alpha-synuclein can cause cell death in the brains of those with Parkinson's disease (PD) by forming clusters (or aggregates) on the surface of small storage... -
Research Grant, 2016LRRK2 Non-coding Variation in Parkinson's Disease
Study Rationale:
Genetic studies looking at differences in DNA have identified key genes that can cause Parkinson's disease (PD) in families and contribute to the overall risk of developing sporadic... -
Target Advancement Program, 2016Alpha-synuclein-induced Astroglial Inflammation as a Trigger of Parkinson's Disease
Study Rationale:
Astrocytes are important cells in the brain. They play a major role in brain inflammation and neurodegeneration; however, their role in Parkinson's disease (PD) is unclear. The protein... -
Target Advancement Program, 2016LRRK2 Kinase Activity and Mitochondrial DNA Damage in Parkinson's Disease
Study Rationale:
LRRK2 is a protein regulated by kinases (protein regulators) and is also subject to autophosphorylation (auto-regulation). Several mutations of LRRK2 increase the kinase activity of...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.