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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Fall 2021 RFP: Outcome Measures, 2022
    Development of Standardized Measurements for Monitoring the Progression of Parkinson’s Disease via MRI

    Study Rationale: One of the difficulties in research towards new treatments in Parkinson’s disease (PD) is the diversity of disease presentations and the lack of tools to measure the effect of a...

  • Biomarkers to Support Therapeutic Trials Program, 2023
    Using Neurophysiology as a Stratification Tool for Synucleinopathy

    Study Rationale: Although numerous disease-modifying drugs are being developed for Parkinson’s disease (PD), the current methods used to identify people suitable for clinical trials are costly...

  • Biosample and Tissue Resource, 2013
    Relationship of Vitamin B12 Status and Parkinson's Disease

    Objective/Rationale:             
    Vitamin B12 deficiency can cause a number of neurological symptoms, including instability, neuropathy (which may cause numbness and tingling) and cognitive defects...

  • MJFF Research Grant, 2011
    fMRI of First Degree Relatives of LRRK2 Positive PD Patients

    Objective/Rationale:

    First, to study the effect of the presence of the LRRK2 G2019S mutation on brain activation patterns in Parkinson’s disease (PD) patients who recently converted into a diseased...

  • Rapid Response Innovation Awards, 2014
    Effect of Dietary Ketosis On Alpha-Synuclein Accumulation

    Study Rationale:
    A key feature of Parkinson’s disease is abnormal accumulation of the protein alpha-synuclein. Production of organic compounds called ketones is a normal metabolic process that occurs...

  • Accelerating Biological Understanding and Therapeutic Translation for PD-Biology, 2025
    GBA1 Consortium: Joint Analysis to Inform Clinical Trials

    Study Rationale: Variants in the GB1A gene represent the most important genetic risk factor for Parkinson’s disease (PD) across the globe. However, different GBA1 variants are associated with varied...

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