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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2014
    Neuroimaging Carriers of the Alpha-synuclein E46K Mutation as a Model of Idiopathic Lewy Body Disease

    Study Rationale:
    In 2004 our group described, for the first time in literature, the E46K mutation of the alpha-synuclein gene in a family from the Basque region of Spain. The rare E46K mutation is...

  • Biomarkers to Support Therapeutic Trials Program, 2023
    Using Neurophysiology as a Stratification Tool for Synucleinopathy

    Study Rationale: Although numerous disease-modifying drugs are being developed for Parkinson’s disease (PD), the current methods used to identify people suitable for clinical trials are costly...

  • Fall 2021 RFP: Outcome Measures, 2022
    Development of Standardized Measurements for Monitoring the Progression of Parkinson’s Disease via MRI

    Study Rationale: One of the difficulties in research towards new treatments in Parkinson’s disease (PD) is the diversity of disease presentations and the lack of tools to measure the effect of a...

  • ASAP CRN Competitive Renewal Opportunity, 2024
    Understanding and Manipulating Cellular and Circuit-level Vulnerability to Neurodegeneration in Parkinson’s Disease
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    Study Rationale: Many people with Parkinson’s disease (PD) develop untreatable cognitive symptoms due to changes in the brain’s cerebral cortex. These symptoms, which include problems with attention...

  • Biosample and Tissue Resource, 2013
    Relationship of Vitamin B12 Status and Parkinson's Disease

    Objective/Rationale:             
    Vitamin B12 deficiency can cause a number of neurological symptoms, including instability, neuropathy (which may cause numbness and tingling) and cognitive defects...

  • MJFF Research Grant, 2011
    fMRI of First Degree Relatives of LRRK2 Positive PD Patients

    Objective/Rationale:

    First, to study the effect of the presence of the LRRK2 G2019S mutation on brain activation patterns in Parkinson’s disease (PD) patients who recently converted into a diseased...

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