The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Improved Biomarkers and Clinical Outcome Measures, 2016Supramolecular Hosts as Combined Protein Aggregation Inhibitors and Hyperpolarized MRI Reporters
Study Rationale:
Amyloid fibrils play a key role in Parkinson's disease (PD) and monitoring of their formation from self‐assembled insoluble molecular aggregates would be extremely valuable as a... -
Access to Data and Biospecimens, 2016Evaluation of Glucocerebrosidase Pathway Biomarkers in Parkinson's Disease
Study Rationale:
Parkinson disease (PD) due to monoallelic glucocerebrosidase (GBA1) gene mutations (GBA-PD) is at the forefront of novel approaches to the treatment of PD. Exciting potential...
-
Research Grant, 2016Identification of Epigenetic Signatures in Blood as Biomarkers for Parkinson's Disease
Study Rationale:
Epigenetic processes (changes in gene expression), such as DNA methylation (mechanism that cells use to control gene expression), ensure proper functioning of genetic materials in... -
Biomarker Development, 2015Development of Novel, Small Molecule Compounds as PET Tracers for Synucleinopathies
Study Rationale:
Our project aims to develop a brain imaging agent for alpha-synuclein, a key protein involved in Parkinson’s disease (PD) pathology. Such an agent will help (i) diagnose PD earlier,... -
Access to Data and Biospecimens, 2015Lysosomal Enzyme Activity and GBA1 Genotyping in Parkinson’s Disease
Study Rationale:
The dysfunction of the systems responsible for the clearance of the protein alpha-synuclein plays a major role in Parkinson’s disease (PD). The lysosome is an... -
Therapeutic Pipeline Program, 2015Utilization of Aptamers to Prevent Protein Aggregation in Parkinson’s Disease
Objective/Rationale:
The abnormal aggregation of a protein known as alpha-synuclein appears to play a critical role in Parkinson's disease. This project will explore a new type of...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.