The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Target Validation, 2014Seeking Neuroprotection via a Novel Complex-1 Chaperone
Objective/Rationale:
Mitochondria are the powerplants of the cell, and decades of evidence suggest that they may be defective in the brains of people with Parkinson’s. The overall goal of... -
Therapeutic Pipeline Program, 2014Evaluation of the Oligomer Modulator anle138b in a Seeding-based Model of Parkinson’s Disease
Objective/Rationale:
Mounting evidence indicates a crucial role of pathological aggregates of the protein alpha-synuclein in Parkinson’s disease (PD). Small aggregates termed oligomers... -
Target Validation, 2014Targeting the Stress Sensor PERK for the Treatment of Parkinson´s Disease
Objective/Rationale:
Parkinson's disease (PD) is characterized by impairment of motor control as a result from extensive neuron death. The primary mechanism responsible for the progressive... -
Improved Neuromodulation Approaches, 2014Optogenetic Restoration of Basal Ganglia Function to Treat Parkinson’s Disease
Study Rationale:
Optogenetics has gained wide interest as a tool to understand the function of circuits influencing brain diseases. This approach uses proteins that respond to... -
Improved Neuromodulation Approaches, 2014Machine Learning for Programming Deep Brain Stimulation Arrays
Study Rationale:
Deep brain stimulation (DBS) implants for treating Parkinson’s disease currently consist of four round electrodes stacked along a thin cylindrical carrier lead. When... -
Improved Neuromodulation Approaches, 2014Multicenter Clinical Trial of Deep Brain Stimulation in Early Stage Parkinson’s Disease
Study Rationale:
Deep brain stimulation (DBS) is an effective treatment for many patients with advanced stage Parkinson’s disease (PD) when symptoms are not adequately controlled with medication...
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Our funding programs support basic, translational and clinical research from academia and industry.