The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Parkin Biology, 2014Role of Parkin in Innate Immunity
Objective/Rationale:
The protein Parkin contributes to the elimination of damaged mitochondria by a process called mitophagy. Prior research has shown that silencing Parkin gene affects innate immunity... -
Rapid Response Innovation Awards, 2014The Microbiome in Parkinson's Disease: Role as a Potential Biomarker and Relation to Disease Progression
Promising Outcomes of Original Grant:
In their previous study these researchers investigated whether the abundance of different microbes in the gut differs between Parkinson’s disease (PD) patients and... -
Rapid Response Innovation Awards, 2014Parc (a Parkin-related E3 Ligase): Functions in Neuronal Survival and Parkinson’s Disease
Objective/Rationale:
Parkinson’s disease (PD) is frequently associated with mutations in the gene that encodes Parkin, a protein that detects and degrades dysfunctional mitochondria. While removing... -
Research Grant, 2014Anti-dyskinetic Activity of the Selective 5-HT1A Agonist NLX-112: Behavioral and Microdialysis Studies
Promising Outcomes of Original Grant:
These researchers are investigating the activity of novel drugs that potently activate serotonin 5-HT1A receptors. Targeting this receptor subtype is an attractive... -
Access to Data and Biospecimens, 2014Effect of LRRK2 Mutations on PD-associated Inflammation
Objective/Rationale:
Increased inflammation is associated with the progression and possibly even onset of Parkinson’s disease (PD). Mutations in the LRRK2 gene are also associated with PD, and recent... -
Access to Data and Biospecimens, 2014Defining Non-motor Phenotypes in Parkinson’s Disease and Novel Strategies for Diagnosis
Objective/Rationale:
Although Parkinson’s disease (PD) is diagnosed as a movement disorder, motor deficits are preceded by non-motor features including cognitive, cardiovascular, gastrointestinal...
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Our funding programs support basic, translational and clinical research from academia and industry.