The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Alpha-synuclein Pathology, 2014Characterization and Validation of Disease-specific Alpha-synuclein Species in Cerebrospinal Fluid
Study Rationale:
The protein alpha-synuclein plays a major role in Parkinson’s disease (PD). Quantification of alpha-synuclein in biological fluids (e.g., cerebrospinal fluid) could... -
Access to Data and Biospecimens, 2014Purine Biomarkers of LRRK2 PD
Objective/Rationale:
Oxidative damage to brain cells — akin to rust on car parts — can build up in Parkinson’s disease (PD) and leads to break down of brain functions. Urate is a natural... -
Access to Data and Biospecimens, 2014LRRK2 in Urine as a Biomarker for PD
Objective/Rationale:
A mutation in the LRRK2 gene is the most common known genetic cause of Parkinson’s disease (PD). Not everyone who has the LRRK2 mutation will develop PD, but there are... -
Rapid Response Innovation Awards, 2014Role of Parkin and Its Opponent in Parkinson’s Disease Onset
Study Rationale:
Parkin is an enzyme that adds molecules to proteins, including one called mitofusin, which bridges mitochondria (cell’s powerhouse) to the endoplasmic reticulum (structure... -
Research Grant, 2014Validation of the Movement Disorders Society’s Clinical Criteria of Parkinson’s Disease
Study Rationale:
Diagnosis of Parkinson’s disease (PD) and other causes of parkinsonism is not always an easy task for physicians. An accurate diagnosis, however, is an essential aspect of care for... -
Rapid Response Innovation Awards, 2014Rating Segmental Progression of Cardinal Motor Symptoms in Early Parkinson's Disease
Objective/Rationale:
We recently reported a new, practical approach to rate segmental progression of cardinal motor symptoms in Parkinson's disease (PD) at early stages. We computed four new scores —...
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Our funding programs support basic, translational and clinical research from academia and industry.