The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2014Cofilin-1 as a Major Contributor to Oxidative Stress-mediated Cell Death in Parkinson’s Disease
Objective/Rationale:
Oxidative stress, a process that stops the cell producing energy efficiently, is a key cause of the death of neurons in Parkinson’s disease. We have previously shown that oxidative... -
Therapeutic Pipeline Program, 2014Characterization of a Novel Therapy To Selectively Silence Alpha-Synuclein In Monoaminergic Neurons
Objective/Rationale:
The biotech company nLife Therapeutics has designed a molecule (NLF-PD-1233) to target specific neurons in the brain to reduce expression of the protein alpha-synuclein (which... -
Rapid Response Innovation Awards, 2014Electromyography Signals as Biomarkers for Parkinson’s Disease
Objective/Rationale:
A simple, painless and reliable method to detect Parkinson’s disease at an early stage is very important to patients, doctors and researchers. Doctors want to help patients early... -
Research Grant, 2014Clinical and Neuroimaging Predictors of Cognitive Decline in Parkinson’s Disease
Objective/Rationale:
Parkinson’s disease (PD) dementia is often preceded by a phase of mild cognitive impairment (PD-MCI), for which diagnostic criteria have been recently proposed. However, there... -
Access to Data and Biospecimens, 2014CRP40 Expression as a Biomarker of Parkinson’s Disease
Objective/Rationale:
Alterations in HSPA9 gene expression has been described in Parkinson’s disease (PD). Ongoing studies suggest the expression of CRP40, a gene product of HSPA9, in the... -
Access to Data and Biospecimens, 2014Diffusion Tensor-based Biomarker for Parkinson's Disease
Objective/Rationale:
Magnetic resonance imaging (MRI) is a common tool used to diagnose or evaluate brain diseases such as Parkinson’s disease. Typically, MRI images are read by a...
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Our funding programs support basic, translational and clinical research from academia and industry.