The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2013Near Infrared Chronic Intracranial Illumination for Neuroprotection in Parkinson's Disease
Objective/Rationale:
The treatment of Parkinson’s Disease (PD) is based on medication and on surgical procedures. These therapies alleviate symptoms but do not change the evolution of the... -
Rapid Response Innovation Awards, 2013Glycosylation as an Inhibitor of Alpha-synuclein Aggregation
Objective/Rationale:
During the development of Parkinson’s disease the protein alpha-synuclein forms toxic clumps, or aggregates, that have been demonstrated to directly contribute to the... -
Rapid Response Innovation Awards, 2013Investigation of the Contribution of Copy Number Alterations in Parkinson’s Disease Genes to Pathogenesis
Objective/Rationale:
In most cases, the cause of Parkinson’s disease (PD) is unknown. Testing blood for DNA mutations is usually negative, but there is increasing evidence that DNA can... -
LRRK2 Challenge, 2013Functional Analysis of LRRK2 Phosphorylation in Human Dopaminergic Neurodegeneration
Objective/Rationale:
Although mutations in LRRK2 are the most common genetic cause of Parkinson’s disease (PD) known, the molecular mechanism is unclear. LRRK2 protein is phosphorylated (addition of a... -
Research Grant, 2013Kinase Activity in Lymphocytes
Objective/Rationale:
It has been suggested that the G2019S mutation in the LRRK2 gene leads to increased kinase (a type of enzyme) activity. Previous work has been conducted in cultured cells... -
Research Grant, 2013Phenylbutyrate for Alpha-synuclein Clearance from the Brain
Objective/Rationale:
In our previous research, we have discovered that a drug called phenylbutyrate can turn on a protective gene in the brain and can prevent Parkinson’s disease (PD) in...
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Our funding programs support basic, translational and clinical research from academia and industry.