The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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MJFF Research Grant, 2011Development and Test of a P25a Competitive Alpha-synuclein Aggregate Binding Assay and Test of Thioflavin-T as Competitor
Objective/Rationale:
Compounds targeting aggregated alpha-synuclein are high in demand as potential bio-imaging tools. We have previously developed an assay that measures the binding of the protein... -
MJFF Research Grant, 2011Just in Time Pre-clinical Resource for Evaluating Symptoms & Side Effects and/or Dyskinesia Treatments
Objective/Rationale:
There is a clear need for the development of novel treatments to better manage the symptoms of Parkinson’s disease. While current treatments address some of the motor symptoms of... -
MJFF Research Grant, 2011Generation of Synthetic Alpha-synuclein for the PD Research Community
Objective/Rationale:
Despite increasing evidence linking specific modifications to alpha-synuclein (alpha-syn), alpha-synuclein aggregation, and Lewy body (LB) formation, little is still known... -
LRRK2 Target Engagement Ligand, 2011Discovery of LRRK2 Target Engagement Ligands to be Used in Imaging Studies
Objective/Rationale:
LRRK2 is an emerging target for discovery of a neuroprotective agent for treatment of PD. Multiple mutations within the LRRK2 gene are associated with PD and many of these have... -
LRRK2 Target Engagement Ligand, 2011LRRK2 Target Engagement Ligand
Objective/Rationale:
Target engagement ligands, also known as imaging agents, are useful tools in the development of drugs and this project seeks to develop such a tool for Leucine Rich Repeat Kinase... -
Rapid Response Innovation Awards, 2011Regulated GDNF Gene Therapy: a Novel Regulatory System Based on Protein Degradation
Objective/Rationale:
Gene therapy may offer effective treatments to patients. Delivering genes to cells in the body has the potential of letting the patient’s cells treat themselves. In the case of...
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Our funding programs support basic, translational and clinical research from academia and industry.