The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Repositioning Drugs for PD, 2012Atomoxetine for Cognitive Impairment in Parkinson’s Disease
Objective/Rationale:
Parkinson’s disease (PD) causes well known motor symptoms of tremor, slowness and stiffness, but also leads to cognitive impairment. Research has shown that early loss of cells in... -
Research Grant, 2020GBA Variations, Cholinergic Degeneration, and Cognitive Decline in Parkinson’s Disease
Study Rationale:
Mutations in the GBA gene are the most common genetic risk factors for Parkinson’s disease. People with GBA mutations (GBA-PD) may develop the disease at a younger age and may have... -
Research Grant, 2011Comparing Cognitive Scales in the MUSTARDD-PD Study
Objective/Rationale:
Some people with Parkinson’s may develop dementia during their disease course. Being able to detect problems with mental function at an early stage, to monitor and to reliably... -
Research Grant, 2013Validation of the Movement Disorders Society Criteria for Mild Cognitive Impairment in Parkinson’s Disease
Objective/Rationale:
Dementia in Parkinson’s disease (PD) is a serious health issue and a major concern for many PD patients. Mild cognitive impairment (MCI) is considered a transitional... -
Cognition Biomarkers, 2013Validation of Computer-based Saccade Measures as a Biomarker for Neurocognitive Changes in Parkinson's Disease
Objective/Rationale:
Saccades are fast eye movements that shift visual focus for tasks like reading, visual searching and coordinating safe movement. Research has shown that the speed, accuracy and... -
Research Grant, 2012Phase I-B Clinical Trial of AVE8112 for Cognitive Impairment in Parkinson’s Disease
Objective/Rationale:
Cognitive impairment is a symptom seen in Parkinson’s disease (PD) patients, and some can progress to dementia. AVE8112 is a PDE4 inhibitor that was in development by the...
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Our funding programs support basic, translational and clinical research from academia and industry.